Search results (18)
« Back to PublicationsInterindividual variability in immune response to AAV ocular gene delivery across species impedes immunomonitoring
Journal article
Ren D. et al, (2026), JCI Insight, 11
Ocular gene therapy mediated by AAV vectors: an overview of immunosuppressive treatments and immunomonitoring of patients involved in clinical trials
Journal article
Ren D. et al, (2026), Progress in Retinal and Eye Research, 111, 101443 - 101443
AAV-delivered CRISPR-Cas9 elicits persistent retinal immune responses compared with transient responses to RNP
Preprint
Pulman J. et al, (2025)
Inducible nonhuman primate models of retinal degeneration for testing end-stage therapies
Journal article
Ail D. et al, (2023), Science Advances, 9
Adeno-Associated Virus (AAV) - Based Gene Therapies for Retinal Diseases: Where are We?
Journal article
Ail D. et al, (2023), The Application of Clinical Genetics, Volume 16, 111 - 130
Pre-existing neutralizing antibodies against different adeno-associated virus serotypes in humans and large animal models for gene therapy (Preprint)
Preprint
Ail D. and Dalkara D., (2022)
Immune Responses to Gene Editing by Viral and Non-Viral Delivery Vectors Used in Retinal Gene Therapy
Journal article
Ren D. et al, (2022), Pharmaceutics, 14, 1973 - 1973
Stanniocalcin2, but Not Stanniocalcin1, Responds to Hypoxia in a HIF1-Dependent Manner in the Retina
Journal article
Ail D. et al, (2022), Frontiers in Neuroscience, 16
Systemic and local immune responses to intraocular AAV vector administration in non-human primates
Journal article
Ail D. et al, (2022), Molecular Therapy - Methods & Clinical Development, 24, 306 - 316
Linking YAP to Müller Glia Quiescence Exit in the Degenerative Retina
Journal article
Hamon A. et al, (2019), Cell Reports, 27, 1712 - 1725.e6
Hif1a inactivation rescues photoreceptor degeneration induced by a chronic hypoxia-like stress
Journal article
Barben M. et al, (2018), Cell Death & Differentiation, 25, 2071 - 2085
Müller glial cell reactivation in Xenopus models of retinal degeneration
Journal article
Langhe R. et al, (2017), Glia, 65, 1333 - 1349
Retinal Degeneration and Regeneration—Lessons From Fishes and Amphibians
Journal article
Ail D. and Perron M., (2017), Current Pathobiology Reports, 5, 67 - 78