Search results (17)
« Back to PublicationsMicroglia in C9orf72–associated amyotrophic lateral sclerosis: More or less active?
Journal article
Vahsen BF. and Pasterkamp RJ., (2026), Neural Regeneration Research
Telmisartan is neuroprotective in a hiPSC-derived spinal microtissue model for C9orf72 ALS via inhibition of neuroinflammation
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Sonustun B. et al, (2025), Stem Cell Reports, 20, 102535 - 102535
Extracellular vesicles in TDP-43 proteinopathies: pathogenesis and biomarker potential
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Dellar ER. et al, (2025), Molecular Neurodegeneration, 20
High-throughput screen of 100 000 small molecules in C9ORF72 ALS neurons identifies spliceosome modulators that mobilize G4C2 repeat RNA into nuclear export and repeat associated non-canonical translation
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Luteijn MJ. et al, (2025), Nucleic Acids Research, 53
Dynactin-1 mediates rescue of impaired axonal transport due to reduced mitochondrial bioenergetics in amyotrophic lateral sclerosis motor neurons
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Dafinca R. et al, (2024), Brain Communications, 6
Recent insights from human induced pluripotent stem cell models into the role of microglia in amyotrophic lateral sclerosis
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Nikel LM. et al, (2024), BioEssays, 46
Cellular and axonal transport phenotypes due to the C9ORF72 HRE in iPSC motor and sensory neurons
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Scaber J. et al, (2024), Stem Cell Reports, 19, 957 - 972
Neuro‐immune interactions in health and disease: Insights from FENS‐Hertie 2022 Winter School
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Binder LB. et al, (2024), European Journal of Neuroscience, 59, 1977 - 1992
C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9
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Vahsen BF. et al, (2023), Nature Communications, 14
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
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Vahsen BF. et al, (2022), Scientific Reports, 12
Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation
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Giacomelli E. et al, (2022), Cell Stem Cell, 29, 11 - 35
Non-neuronal cells in amyotrophic lateral sclerosis — from pathogenesis to biomarkers
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Vahsen BF. et al, (2021), Nature Reviews Neurology, 17, 333 - 348
AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo
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Ribas VT. et al, (2021), Cell Death & Disease, 12
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
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Klionsky DJ. et al, (2021), Autophagy, 17, 1 - 382
ULK1 as a novel therapeutic target in neurodegeneration
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Lingor P. and Vahsen B., (2021), Neural Regeneration Research, 16, 1212 - 1212