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UK Biobank is an on-going prospective epidemiological study that has already collected genetics, blood, lifestyle information and other data from a cohort of 500,000 subjects, to be followed over coming decades. The "UK Biobank Imaging Extension", which aims to bring back 100,000 of the cohort for multimodal neuroimaging and cardiac MRI (amongst other measures), has just been given the go-ahead. This will be by far the largest neuro/cardiac imaging study carried out to date, and will add very rich phenotyping to the project.