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Old Age Neuroscience and the ORCHARD portfolio
We lead the assembly of well-characterised clinical cohorts of hospital patients to study the burden and outcomes of cognitive and physical frailty, develop risk prediction algorithms for delirium and dementia combining both clinical and brain imaging data, and undertake mechanistic studies of delirium and dementia following acute illness for translational impact.
Translational Neuropsychology Group
Stroke survivors often experience changes in their thinking abilities (cognition). Our aims are to improve the detection of post-stroke cognitive changes and to improve the cognitive support available for stroke survivors.
Large Artery Disease
CPSD runs several research studies looking into the causes, investigation, and management of large artery atherosclerosis, carotid stenosis, vertebral artery disease and intracranial atherosclerosis.
OPTIMA
The Oxford Project to Investigate Memory and Ageing (OPTIMA) started in 1988 and the last LEAD participants were seen in March 2015. We are no longer recruiting to any of the cohorts. However, we are currently creating the OPTIMA Legacy Resource from which data collected from the OPTIMA cohorts is available and samples are biobanked and available. Brain tissue is available as part of the Brains For Dementia Research (BDR) collection.
Oxford Vascular Study
The Oxford Vascular Study (OxVasc) investigates vascular diseases (e.g. strokes, heart attacks) in patients registered with eight general practices in Oxfordshire. We run a rapid-access clinic for patients with suspected Transient Ischaemic Attacks (TIAs) or minor strokes. All OxVasc clinics held in the Wolfson Centre for the Prevention of Stroke and Dementia follow Oxford University Hospitals NHS Foundation Trust infection control guidelines.