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FMRIB Neurodegeneration Group
FMRIB’s Neurodegeneration group comprises clinical and basic neuroscientists across a range of departments and disciplines with a common interest in using neuroimaging to understand normal ageing and disease processes.
Computational Neuroscience
We investigate anatomical organisation and cortical processing using computational models and techniques.
FMRI Acquisition and Reconstruction
We develop image acquisition and reconstruction techniques for functional MRI. These methods aim to provide higher spatial and temporal resolution, as well as greater sensitivity to brain activity.
Microstructural Imaging
The fine-scale structure of brain tissue is crucial to neural function and health. We are developing MRI techniques that may enable non-invasive estimates of brain microstructure.
MR Spectroscopy
We develop new ways to measure metabolically active chemicals with MRI in order to understand the dynamic chemistry of the human brain. Our particular interests are in "multi-voxel" or spectroscopic imaging, and measuring dynamically changing processes. We create new MR techniques and publish software to do this.
Multiple Sclerosis Clinical Trials Unit
The Multiple Sclerosis and Related Disorders Clinical trials unit is a hybrid unit combining the strengths and longstanding research tradition from both Oxford University and Oxford University Hospitals.
Neurodegeneration and Inflammation Research Group
We explore the neuropathology of multiple sclerosis and other inflammatory and neurodegenerative diseases using a multidisciplinary team approach to post-mortem brain and spinal cord tissue. The aim is that the understanding derived from these studies will translate into ideas for improved treatments for living patients.
Neuromuscular Disorders
We work to translate an understanding of the molecular mechanisms of disease at the neuromuscular synapse into treatments. Our work led us to be commissioned to provide a National Advisory and Diagnostic Service for congenital myasthenic syndromes.
Congenital Myasthenia Service
We provide a nationally commissioned specialised service for the diagnosis and management of children and adults in whom a congenital myasthenic syndrome is suspected.