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Gwenaëlle Douaud and colleagues reveal new evidence that shows how development, ageing, and disease processes are related in the brain.
Cognitive Neuroanatomy
FMRIB
Old Age Neuroscience and the ORCHARD portfolio
CPSD
We lead the assembly of well-characterised clinical cohorts of hospital patients to study the burden and outcomes of cognitive and physical frailty, develop risk prediction algorithms for delirium and dementia combining both clinical and brain imaging data, and undertake mechanistic studies of delirium and dementia following acute illness for translational impact.
Oxford Stroke Recovery Research Hub
The Oxford Stroke Recovery Research Hub is a network of research groups and clinical collaborators with a shared interest in stroke recovery research.
Translational Neuropsychology Group
CPSD
Stroke survivors often experience changes in their thinking abilities (cognition). Our aims are to improve the detection of post-stroke cognitive changes and to improve the cognitive support available for stroke survivors.
Pain and Aversive Learning
FMRIB
We aim to understand how the brain processes pain, with a particular focus on computation and information processing.
Oxford Neurotheory
A collaborative effort between several departments at the University of Oxford to study theoretical and computational neuroscience.
Neuromusculoskeletal Health and Science Lab
DCN
We use a translational and interdisciplinary approach to study the pathophysiology of neuromusculoskeletal conditions with the ultimate goal to improve management for patients.
Ventilator Weaning and Extubation in Neurocritical Care Network
NDA
How can we get patients safely off the ventilators following a traumatic brain injury or neurosurgery? How do we plan to avoid unnecessary re-intubations and prolonged ventilation? How could we reduce ventilator days and length of stay in ICU?
Dynamic Neuromodulation
MRC BNDU
Retinal Disease and Repair (Xue Lab)
NLO
The Xue Lab is a translational research group investigating the mechanisms of retinal inflammation and degeneration in the context of age-related macular degeneration (AMD), uveitis and retinal gene therapy. Our aim is to translate improved understanding of disease mechanisms into clinical trials for patients with retinal diseases, and ultimately new therapies to prevent sight loss.
Diseases of Protein Glycosylation
DCN
Glycosylation is one of the most common and poorly understood forms of post-translational modification. Our aim is to understand the biochemical mechanisms underlying protein glycosylation, as well as decipher the roles that they play in health and disease.
Anaesthesia Neuroimaging Group
NDA
Our group uses multimodal neuroimaging to understand the changes in the brain under anaesthesia and during altered states of consciousness. We aim to translate these findings to the clinical environment to improve patient treatment and outcomes.
Oxford University Global Surgery Group
The Oxford University Global Surgery Group brings together Medical Sciences Division clinicians in surgery, anaesthesia, obstetrics and gynaecology with an interest in global surgical issues.
Computational Neurology
DCN NDCN
Our group applies computational models to study changes in motivation, memory and decision-making that occur in neurological disease. We combine behavioural, neuroimaging, and pharmacological experiments to apply mathematical models to clinical problems.
Experimental and Clinical Sleep Medicine
The Experimental and Clinical Sleep Medicine group is jointly led by Professor Colin Espie and Professor Simon Kyle. Our research aims to 1) elucidate the mechanisms underpinning chronic sleep disruption; 2) understand the role of sleep disruption in driving adverse health outcomes; and 3) develop interventions to treat sleep and circadian rhythm disruption. We conduct human experimental and clinical studies on sleep and disorders of sleep. Our research programme is supported by the National Institute of Health Research through the Oxford Biomedical Research Centre, Health Technology Assessment Programme, and Efficacy and Mechanisms Evaluation Programme, and the Dr. Mortimer and Theresa Sackler Foundation, amongst others.
Oxford Centre for Neuroinflammation
DCN
We bring together biomedical, analytical and clinical expertise to shed new light on the causes that underpin neurodegenerative diseases.