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We study how the brain changes when we learn, as we get older, or when we recover damage such as stroke. We use brain imaging to monitor brain change and we aim to develop new approaches to facilitate learning, recovery and healthy brain development and ageing.
Risk factors for faster aging in the brain revealed in new study
Clinical Neurology Publication Research
25 April 2024
Researchers from the NDCN have used data from UK Biobank participants to reveal that diabetes, traffic-related air pollution and alcohol intake are the most harmful out of 15 modifiable risk factors for dementia.
Congratulations to Linxin Li
Award Research Stroke & Dementia
27 March 2024
Who has been awarded a prestigious fellowship.
Patient Safety Commissioner for England visits our simulation centre
Anaesthetics Research Teaching
19 February 2024
Dr Henrietta Hughes, the Patient Safety Commissioner for England, visited the Oxford Simulation, Teaching and Research Centre (OxSTaR) at the John Radcliffe Hospital on Friday 16 February.
New study finds Anaesthesia Associates not economically viable
Anaesthetics Research
12 February 2024
An in-depth economic analysis by a multi-national research group has concluded that the productivity gained by using Anaesthesia Associates in operating theatres are very modest and do not justify the salaries currently being paid.
New research shows that online testing is effective in detecting cognitive impairments in complex neurological diseases
Clinical Neurology Publication Research
5 February 2024
The Cognitive Neurology Research Group at the Nuffield Department of Clinical Neurosciences has shown that remote digital cognitive testing can detect subtle cognitive impairments in chronic autoimmune limbic encephalitis (ALE) patients.
Research uncovers mechanism behind stubborn memories
MRC BNDU Research
18 January 2024
Researchers from the Medical Research Council Brain Network Dynamics Unit at the University of Oxford and the Nuffield Department of Clinical Neurosciences have identified a novel mechanism by which the brain produces powerful lasting memories that drive ill-advised actions. Focusing on cocaine experience, the researchers demonstrate how the collective activity of many nerve cells distributed across the brain underlies the persistence of such memories, providing new insights into why drug-seeking behaviours could lead to addiction.
Research into ancient DNA sheds new light on cause of Multiple Sclerosis and other neurodegenerative diseases
Clinical Neurology Research
11 January 2024
Research led by scientists at the Universities of Oxford, Cambridge, Copenhagen, Bristol and California (Berkeley) reveals the evolutionary origins of multiple sclerosis (MS). This new insight into the genetic architecture of this disease changes scientists’ view of its causes and has implications for its treatment, as well as paving the way for further investigations into other diseases.
New research shows that the way the brain learns is different from and better than the way that artificial intelligence systems learn
Clinical Neurology Research
3 January 2024
Researchers from the MRC Brain Network Dynamics Unit and Oxford University's Department of Computer Science have set out a new principle to explain how the brain adjusts connections between neurons during learning.
New MRI research reveals more about the effects of two movement disorders on sensorimotor functional connection
Clinical Neurology Integrative Neuroimaging Research
18 December 2023
Our researchers have shown for the first time non-invasively in humans a differential, clinically meaningful impact of Huntington’s and Parkinson’s diseases on the sensorimotor functional connection of the subthalamic nucleus and sensorimotor cortex.
Researchers develop a blood test to identify individuals at risk of developing Parkinson’s disease
Clinical Neurology Research
5 December 2023
Research carried out at the University of Oxford has led to the development of a new blood-based test to identify the pathology that triggers Parkinson’s disease before the main symptoms occur. This could allow clinicians to screen for those individuals at high risk of developing the disease and facilitate the timely introduction of precision therapies that are currently at clinical trial stage.
Finnish Ambassador visits our Department
Clinical Neurology Research Teaching
7 November 2023
NDCN hosted a networking event with a delegation from the Finnish embassy and a group of University of Oxford students from Finland.
New fellowships in brain science established with philanthropic support
Clinical Neurology Research
30 October 2023
Wearable sensors provide early detection of progression in Parkinson’s Disease
Clinical Neurology Research
9 October 2023
A team of researchers from the University of Oxford has shown for the first time that it is possible to track the progression of Parkinson’s Disease accurately using specially trained machine learning algorithms to analyse data derived from sensor devices worn by patients.
Gene therapy opens new possibilities for treating chronic pain
Clinical Neurology Research
5 October 2023
Our researchers have shown the potential of a new gene therapy approach to silence human sensory neurons as a means of treating persistent pain. Many current drugs for chronic pain are highly addictive, which makes it important to discover new alternatives.
Six New Professors
Research
8 September 2023
Many congratulations to the following members of our Department who have been awarded the title of Professor in the recent Recognition of Distinction round.
PAINCAST: A new collaborative podcast exploring the experience of neuropathic pain
Clinical Neurology Research
7 September 2023
PAINCAST: Neuropathic Pain Unravelled, a creative podcast about living with long-term pain, is part of a ground-breaking four-year collaborative research project into neuropathic pain.
Understanding the immune response in people with myasthenia gravis
Clinical Neurology Research
5 September 2023
Muscular Dystrophy UK has announced that it is investing £1.3 million into 11 new research projects including one at the University of Oxford.
Brief sleep therapy delivered by nurses improves insomnia
Ophthalmology Research SCNi
11 August 2023
Researchers from the University of Oxford have found that a brief form of cognitive behavioural therapy (CBT) for insomnia, delivered by nurses in GP surgeries, significantly improves sleep and quality of life compared to sleep hygiene alone.
NDCN groups gain LEAF accreditation for sustainable research
Research
14 July 2023
Several of our research groups have been accredited by the Laboratory Efficiency Assessment Framework (LEAF).
New imaging method trialled for retinal diseases
Ophthalmology Research
28 June 2023
Clinical scientists in Oxford have presented a new method of imaging of the retina that overcomes many of the drawbacks of the current standard way of diagnosing and monitoring retinal diseases like age-related macular degeneration (AMD).
