Contact information
Simon Kyle
MA (First Class Hons.), PhD
Professor of Experimental and Clinical Sleep Research
- Programme Director, The Oxford Online Programme in Sleep Medicine
- Co-Director, Experimental and Clinical Sleep Medicine
- Honorary Member, Department of Psychiatry
- Senior Research Fellow, Somerville College
Sleep, sleep disorders and their treatment
I have specific research interests in the aetiology and management of sleep disturbance and the interaction between sleep disturbance and mental health.
My research is funded by The National Institute for Health and Care Research (NIHR) Oxford Health Biomedical Research Centre (BRC), Health Technology Assessment (HTA) Programme, Programme Grants for Applied Research (PGfAR), Efficacy and Mechanisms Evaluation (EME) Programme and the Wellcome Trust.
Research groups
Websites
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Kavli Institute for Nanoscience Discovery
Research centre
Key publications
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Clinical and cost-effectiveness of nurse-delivered sleep restriction therapy for insomnia in primary care (HABIT): a pragmatic, superiority, open-label, randomised controlled trial
Journal article
KYLE S., (2023), The Lancet
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The sleep-circadian interface: a window into mental disorders
Journal article
Meyer N. et al, (2024), Proceedings of the National Academy of Sciences of USA
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Biological and clinical insights from genetics of insomnia symptoms
Journal article
Lane JM. et al, (2019), Nature Genetics, 51, 387 - 393
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The effect of sleep restriction therapy for insomnia on sleep pressure and arousal: a randomized controlled mechanistic trial
Journal article
Maurer LF. et al, (2021), Sleep
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A Randomized, Placebo-Controlled Trial of Online Cognitive Behavioral Therapy for Chronic Insomnia Disorder Delivered via an Automated Media-Rich Web Application
Journal article
Espie CA. et al, (2012), Sleep, 35, 769 - 781
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The effect of sleep continuity disruption on multimodal emotion processing and regulation: a laboratory‐based, randomised, controlled experiment in good sleepers
Journal article
Reid MJ. et al, (2023), Journal of Sleep Research, 32
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Sleep and cognitive performance: cross-sectional associations in the UK Biobank
Journal article
Kyle SD. et al, (2017), Sleep Medicine, 38, 85 - 91
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The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.
Journal article
Riemann D. et al, (2023), J Sleep Res, 32
Recent publications
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Shift workers’ experiences and views of sleep disturbance, fatigue and healthy behaviors: a systematic review and qualitative evidence synthesis
Journal article
Benton JS. et al, (2025), Scandinavian Journal of Work, Environment & Health
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Is it time to revisit the scoring of Slow Wave (N3) Sleep?
Journal article
Davidson S. et al, (2025), SLEEP
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Sleep Health and White Matter Integrity in the UK Biobank.
Journal article
Petri R. et al, (2025), J Sleep Res
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Process evaluation in a randomised controlled trial of DREAMS-START (dementia related manual for sleep; strategies for relatives) for sleep disturbance in people with dementia and their carers.
Journal article
Amador S. et al, (2025), Age Ageing, 54
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Emotional Processing Following Digital Cognitive Behavioral Therapy for Insomnia in People With Depressive Symptoms: A Randomized Clinical Trial.
Journal article
Tamm S. et al, (2025), JAMA Netw Open, 8
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Genome-wide association analysis of composite sleep health scores in 413,904 individuals.
Journal article
Goodman MO. et al, (2025), Commun Biol, 8
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When life-saving measures lead to trauma: Subcapsular hepatic hematoma after CPR
Journal article
Narula J. et al, (2025), Radiology Case Reports, 20, 379 - 383
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The effect of single‐component sleep restriction therapy on depressive symptoms: A systematic review and meta‐analysis
Journal article
Tse KYK. et al, (2024), Journal of Sleep Research, 33
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Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial
Journal article
KYLE S., (2024), The Lancet Healthy Longevity
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Insomnia prehabilitation in newly diagnosed breast cancer patients: Protocol for a pilot, multicentre, randomised controlled trial comparing nurse delivered sleep restriction therapy to sleep hygiene education (INVEST trial)
Journal article
Fleming L. et al, (2024), PLOS ONE, 19, e0305304 - e0305304