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Funded by NIHR to determine causes and outcomes of strokes at age 18-54 years in the UK

Understanding Stroke at Younger Ages

While stroke has become less common in older adults, research by our group and others has shown that the incidence of stroke is increasing among people under the age of 55. The reasons for this trend remain unclear, and its long-term consequences are not yet fully understood.

This study aims to:

  • Understand the burden and long-term impact of stroke in younger adults across the UK.
  • Investigate the contribution of both traditional and emerging risk factors to stroke at younger ages.

Ultimately, our goal is to improve the prevention, diagnosis, and management of stroke in younger adults.

Selected publications

Temporal Patterns in Stroke Recurrence at Younger Ages

Journal article

Nehme A. and Li L., (2026), JAMA Neurology, 83, 601 - 601

The rising incidence of stroke in the young: Epidemiology, causes and global impact

Journal article

Nehme A. and Li L., (2026), International Journal of Stroke, 21, 14 - 23

Diverging Temporal Trends in Stroke Incidence in Younger vs Older People

Journal article

Scott CA. et al, (2022), JAMA Neurology, 79, 1036 - 1036