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Critical Care Atrial Fibrillation Evaluation (CAFE)

Critical care Atrial Fibrillation Evaluation (CAFE) study will bring together the best evidence on which to base improved guidelines for treatment of patients who develop atrial fibrillation on an ICU.

NIHR BRC Studies

Several studies run through the University of Oxford Critical Care Research Group offices are funded by the NIHR Oxford Biomedical Research Centre.


The Critical Care Research Group undertakes a number of studies that are adopted by the NIHR local research network portfolio.

Non-contact vital signs monitoring

The non-contact vital signs monitoring (NVSM) study was a joint collaboration between the Department of Engineering, the Nuffield Department of Clinical Neurosciences, and Oxehealth Ltd.

Predicting AF after Cardiac Surgery - the PARADISE Score. A Clinical Prediction Rule for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery (PARADISE)

The PARADISE study will develop two reliable prediction models to identify which patients are at greatest risk of developing Atrial Fibrillation (AF) following heart surgery.


The PICRAM study is funded by the Health Innovation Challenge Fund, a joint initiative supported by the Department of Health and the Wellcome Trust.


The REcovery FoLlowing Intensive CarE Treatment (REFLECT) research programme was funded by a grant awarded by the NIHR Research for Patient Benefit scheme. The first phase of this work is now complete and the results are being used to inform development of a complex intervention to improve post-ICU ward care.

Renal Replacement Anticoagulant Management (RRAM)

The Renal Replacement Anticoagulant Management (RRAM) study will research the advantages and disadvantages of the two anticoagulant methods for patients with a kidney injury and treated in an ICU

Safer and more efficient vital signs monitoring: an observational study (FOBS)

The FOBS study aims to develop an evidence-based protocol for how frequently observations should be made that will be both safe and achievable across all acute NHS hospitals


The Sleep in the Intensive Care Unit: Lowering Elements of Noise in the Critical Care Environment (SILENCE) research programme was funded by a feasibility study grant awarded by the NIHR Research for Patient Benefit scheme, and was sponsored by the University of Oxford. For all enquires about the SILENCE project please email: The project ended in 2018 and results from the study have been published. See details below.

Kadoorie Centre for Critical Care Research & Education : Research Blog

Members of the University of Oxford Critical Care Research team discuss topics relevant to research methods and dissemination