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We use brain imaging techniques to investigate the human visual system, both in its normal state and in disease and disorder.

Visual area LOC responds to the generation of words in anophthalmic subjects (born without eyes)
Visual area LOC responds to the generation of words in anophthalmic subjects (born without eyes)

The vision group at FMRIB uses magnetic resonance imaging (MRI) to look at the structure, function and connectivity of the human visual system. We are interested in the functioning of the visual system in its ‘normal’ state in sighted individuals, the changes that occur in people who have disorders of the visual system such as visual impairment or binocular dysfunction and the effects of damage or disease. We use multi-modal MRI, including structural, functional and diffusion MRI and magnetic resonance spectroscopy in the human brain to investigate the relationship with visual function. 

One aspect of our research involves investigating how the brain determines the function of a specific region of the brain. In the case of blind subjects who are anophthalmic, in whom the eyes never developed, we are interested in how the visual pathway is recruited by other neural functions. For those who lose visual function later in life, through trauma or a stroke (hemianopia), we have several projects designed to understand the residual function and any re-organisation that occurs to minimise visual deficits (Hannah Willis). Jasleen Jolly and Aislin Sheldon are investigating  the structure, function and neurochemistry of the visual cortex in people with inherited retinal disease, to determine the consequences of degeneration on the brain. 

Dr Betina Ip is investigating how the neurochemistry of the early visual areas interacts with binocular vision. Dr Ivan Alvarez is applying population receptive field (pRF) approaches to multiple areas of neural processing, including contrasting pRFs quantified in different domains, such as motion and depth. 

Selected publications

Take Part in Research Projects

Plasticity in blindness

Are you interested in how your brain works? Blind volunteers needed for magnetic resonance studies of the brain.

Hemianopia and visual cortex damage

We are always looking for patients with damage to the visual cortex.

Control subjects

Please use contact details above if you are interested in taking part in any of our studies as a control subject.

Current Research Projects

Plasticity in blindness

How is the brain reorganised in the absence of light?

Reorganisation and rehabilitation in Hemianopia

What determines the nature of residual visual function in hemianopia and can it be boosted with training and electrical stimulation?

Seeing in 3D

Determining the patterns of activity in subjects with binocular deficits.