MyArchive
- NDCN
Collected from 1980
Over 6,000 samples of blood and thymic tissue
Over 2,000 patients with myasthenia gravis and related conditions
Patient linked meta-data on clinical phenotype and treatments
A project to preserve and share a unique, historic archive of biosamples from individuals with myasthenia gravis with national and international collaborators
Emeritus Professor Nick Willcox and colleagues have built up a store of over 6,000 serum, peripheral blood mononuclear cells and thymic samples from over 2,000 people with myasthenia gravis dating back to 1980, each of which is associated with detailed information on the clinical phenotype and immunotherapy. These samples comprise a unique resource, which has the potential to provide insight into why individuals develop myasthenia gravis and how those people respond to treatments.
MyArchive was established to provide research groups with access to these samples with the aim of answering key research question about disease mechanisms and their trends over time. The governance panel, comprising Dr Adam Handel, Dr Lahiru Handunnetthi, Prof Isabel Leite and Dr Yin Dong, review applications to use MyArchive samples to ensure that individual donor’s samples are used for those experiments most likely to lead to breakthroughs in our understanding or treatment of myasthenia.
We would encourage interested research groups to submit a proposal to the governance panel using the application form, which can be downloaded from this website. MyArchive aims to decide on proposals within 1 month and has established a boilerplate Material Transfer Agreement to expedite sample sharing with collaborators.
MyArchive is generously supported by MyAware funding and we are committed to sharing the results of projects using MyArchive samples with the research community as well as wider public and patient stakeholders.
