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Flora Liuhua Chen

DPhil Student

BBSRC Interdisciplinary Bioscience DTP

I am co-supervised by Professor Esther Becker, Dr Alexander Thompson, and Dr Elizabeth Dellar. My research aims to identify regional patterns of extracellular vesicles (EVs) in the human central nervous system (CNS). EVs have attracted great interests as potential biomarkers for neurological disorders; however, the heterogeneity of CNS-derived EVs remains poorly understood, particularly within the cerebellum. By integrating EV proteomics with physical and biochemical characterisation, I am building a systematic map of CNS-derived EVs. Establishing this foundation will advance our understanding of EV biology in the human brain and support the development of EV-based liquid biopsies for neurological diseases.