Research groups
Taniya Bhardwaj
Postdoctoral Research Associate
Research Summary
My previous research interest in amyloid structures brought me to the Tofari’s lab. My primary aim in my Ph.D. was to investigate the potential of flaviviral and coronaviral proteins to form amyloid aggregates and their interaction with hallmark proteins. Here, I am working on the clearance of alpha-synuclein aggregates and the distant goal is to identify drug candidates to be useful in Parkinson’s disease.
Recent publications
Potential of ADAM 17 Signal Peptide To Form Amyloid Aggregates in Vitro
Journal article
Bhardwaj T. and Giri R., (2023), ACS Chemical Neuroscience, 14, 3818 - 3825
Amyloidogenic proteins in the SARS-CoV and SARS-CoV-2 proteomes
Journal article
Bhardwaj T. et al, (2023), Nature Communications, 14
One microsecond MD simulations of the SARS-CoV-2 main protease and hydroxychloroquine complex reveal the intricate nature of binding
Journal article
Kumar P. et al, (2022), Journal of Biomolecular Structure and Dynamics, 40, 10763 - 10770