Contact information
Simon Kyle
MA (First Class Hons.), PhD
Professor of Experimental and Clinical Sleep Research
- Programme Director, The Oxford Online Programme in Sleep Medicine
- Co-Director, Experimental and Clinical Sleep Medicine
- Honorary Member, Department of Psychiatry
- Senior Research Fellow, Somerville College
- Theme Co-Lead, Better Sleep, NIHR Oxford Health Biomedical Research Centre
Sleep, sleep disorders and their treatment
I have specific research interests in the aetiology and management of sleep disturbance and the interaction between sleep disturbance and mental health.
My research is funded by The National Institute for Health and Care Research (NIHR) Oxford Health Biomedical Research Centre (BRC), Health Technology Assessment (HTA) Programme, Programme Grants for Applied Research (PGfAR), Efficacy and Mechanisms Evaluation (EME) Programme and the Wellcome Trust.

Research groups
Websites
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Kavli Institute for Nanoscience Discovery
Research centre
Key publications
Emotional Processing Following Digital Cognitive Behavioral Therapy for Insomnia in People With Depressive Symptoms
Journal article
Tamm S. et al, (2025), JAMA Network Open, 8, e2461502 - e2461502
Clinical effectiveness of DREAMS START (Dementia Related Manual for Sleep; Strategies for Relatives) versus usual care for people with dementia and their carers: a single-masked, phase 3, parallel-arm, superiority randomised controlled trial
Journal article
Rapaport P. et al, (2024), The Lancet Healthy Longevity, 5, 100635 - 100635
The sleep–circadian interface: A window into mental disorders
Journal article
Meyer N. et al, (2024), Proceedings of the National Academy of Sciences, 121
The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023
Journal article
Riemann D. et al, (2023), Journal of Sleep Research, 32
The effect of sleep continuity disruption on multimodal emotion processing and regulation: a laboratory‐based, randomised, controlled experiment in good sleepers
Journal article
Reid MJ. et al, (2023), Journal of Sleep Research, 32
The effect of sleep restriction therapy for insomnia on sleep pressure and arousal: a randomized controlled mechanistic trial
Journal article
Maurer LF. et al, (2022), Sleep, 45
Biological and clinical insights from genetics of insomnia symptoms
Journal article
Lane JM. et al, (2019), Nature Genetics, 51, 387 - 393
Sleep and cognitive performance: cross-sectional associations in the UK Biobank
Journal article
Kyle SD. et al, (2017), Sleep Medicine, 38, 85 - 91
Randomized, Placebo-Controlled Trial of Online Cognitive Behavioral Therapy for Chronic Insomnia Disorder Delivered via an Automated Media-Rich Web Application
Journal article
Espie CA. et al, (2012), Sleep, 35, 769 - 781
Recent publications
Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement
Journal article
Tse KYK. et al, (2026), SLEEP
Sleep Improvement for Metabolic Health: A Feasibility Trial of a Digital Sleep Treatment in People With Insomnia and Non‐Diabetic Hyperglycaemia
Journal article
Sharman R. et al, (2026), Journal of Sleep Research
The clinical and cost-effectiveness of improving sleep via carer delivered strategies in people with dementia: the DREAMS START parallel multi-centre RCT.
Journal article
Rapaport P. et al, (2026), Health Technol Assess, 30, 1 - 26
ssociations between shift work patterns and sleep disturbance: an analysis of cross-sectional data from UK Biobank
Journal article
Li X. et al, (2026), BMJ Open, 16, e102976 - e102976
THE IMPACT OF WORKING NIGHTS OR ROTATING SHIFTS ON SLEEP-A CROSS-SECTIONAL SURVEY
Journal article
Sugavanam T. et al, (2026), SLEEP MEDICINE, 138
SHIFT WORK SLEEP DISORDER-THE SHIFT-SLEEP PROGRAMME OF WORK
Journal article
Sugavanam T. et al, (2026), SLEEP MEDICINE, 138
DEVELOPING A PRAGMATIC ONLINE BEHAVIOURAL INTERVENTION FOR SHIFT WORK DISORDER IN NHS STAFF
Journal article
Cheung FTW. et al, (2026), SLEEP MEDICINE, 138
Generation of a Free-Living Ground-Truth Validation Dataset for Wearable Measures of Physical Activity, Sedentary Behavior, Sleep, and Heart Rate in Adults (OxWEARS): Protocol for a Cross-Sectional Study
Journal article
Maylor BD. et al, (2025), JMIR Research Protocols, 14, e78779 - e78779
Untangling the mechanisms of sleep restriction therapy
Journal article
Stanyer EC. et al, (2025), SLEEPJ
Sleep Health and White Matter Integrity in the UK Biobank
Journal article
Petri R. et al, (2025), Journal of Sleep Research, 34