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Publications

Clinical Phenotype and Course of PDE6A-Associated Retinitis Pigmentosa Disease, Characterized in Preparation for a Gene Supplementation Trial.

Kuehlewein L. et al, (2020), JAMA Ophthalmol

Immune responses to retinal gene therapy using adeno-associated viral vectors - Implications for treatment success and safety.

Bucher K. et al, (2020), Prog Retin Eye Res

Retinal oedema in central retinal artery occlusion develops as a function of time.

Ochakovski GA. et al, (2020), Acta Ophthalmol, 98, e680 - e684

Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia

Fischer MD. et al, (2020), JAMA Ophthalmology, 138, 643 - 643

Repair of Retinal Degeneration following Ex Vivo Minicircle DNA Gene Therapy and Transplantation of Corrected Photoreceptor Progenitors.

Barnea-Cramer AO. et al, (2020), Mol Ther, 28, 830 - 844

Initial results from a first-in-human gene therapy trial on X-linked retinitis pigmentosa caused by mutations in RPGR

Cehajic-Kapetanovic J. et al, (2020), Nature Medicine, 26, 354 - 359

CHANGES IN RETINAL SENSITIVITY AFTER GENE THERAPY IN CHOROIDEREMIA.

Fischer MD. et al, (2020), Retina, 40, 160 - 168

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial.

Fischer MD. et al, (2019), JAMA Ophthalmol

Macular spatial distribution of preserved autofluorescence in patients with choroideremia

Hariri AH. et al, (2019), British Journal of Ophthalmology, 103, 933 - 937

[The Natural History of Choroideraemia].

Seitz IP. and Fischer MD., (2019), Klin Monbl Augenheilkd, 236, 236 - 243

Re: Song et al., Toxicology and Pharmacology of an AAV Vector Expressing Codon-Optimized RPGR in RPGR-Deficient Rd9 Mice. Hum Gene Ther Clin Dev 2018; 29(4):188–197

MacLaren RE. et al, (2019), Human Gene Therapy Clinical Development, 30, 40 - 40

Individual neural transfer function affects the prediction of subjective depth of focus

Leube A. et al, (2018), Scientific Reports, 8

Humoral Immune Response After Intravitreal But Not After Subretinal AAV8 in Primates and Patients

Reichel FF. et al, (2018), Investigative Opthalmology & Visual Science, 59, 1910 - 1910

Colour discrimination ellipses in choroideremia

Seitz IP. et al, (2018), Graefe's Archive for Clinical and Experimental Ophthalmology, 256, 665 - 673

Gene therapy for the treatment of X-linked retinitis pigmentosa

Martinez-Fernandez De La Camara C. et al, (2018), Expert Opinion on Orphan Drugs, 6, 167 - 177

Subretinal and Intravitreal Retinal Injections in Monkeys

Dauletbekov D. et al, (2018), Retinal Gene Therapy, 251 - 257

AAV8 Can Induce Innate and Adaptive Immune Response in the Primate Eye

Reichel FF. et al, (2017), Molecular Therapy, 25, 2648 - 2660

Superior Retinal Gene Transfer and Biodistribution Profile of Subretinal Versus Intravitreal Delivery of AAV8 in Nonhuman Primates

Seitz IP. et al, (2017), Investigative Opthalmology & Visual Science, 58, 5792 - 5792

High Symmetry of Visual Acuity and Visual Fields in RPGR-Linked Retinitis Pigmentosa

Bellingrath J-S. et al, (2017), Investigative Opthalmology & Visual Science, 58, 4457 - 4457

Subretinal Injection for Gene Therapy Does Not Cause Clinically Significant Outer Nuclear Layer Thinning in Normal Primate Foveae

Ochakovski GA. et al, (2017), Investigative Opthalmology & Visual Science, 58, 4155 - 4155

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