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Clemence Ligneul

Research Associate in Preclinical Neuroimaging

I am a postdoctoral research associate from the Preclinical Imaging Group, and an invited member of the WIN Physics Group. 


I am interested in the microstructural properties of the developing brain. I am currently focusing on the morphological complexification of cerebellar cells during early postnatal development. To achieve this, I use diffusion-weighted MR spectroscopy (DW-MRS), a method that relies on the diffusion of different intracellular brain metabolites. This project was awarded by a WIN seed grant.


I achieved my PhD at MIRCen (CEA, France, 2014-2017), under the direction of Julien Valette, and explored the rodent brain intracellular space by developing diverse DW-MRS methods. We notably showed that the diffusion properties of myo-inositol reflected the astrocytic morphology.

From 2017 to 2019, I worked at the Champalimaud Foundation (Lisbon, Portugal), where I developed functional MR spectroscopy in the mouse upon visual stimulation