Recent publications
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The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists
Journal article
Napier S. et al, (2011), Bioorganic & Medicinal Chemistry Letters, 21, 3163 - 3167
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Investigating the potential role of oestrogen receptor beta (ER Beta) in affective disorders
Journal article
Irving NG. et al, (2006), JOURNAL OF AFFECTIVE DISORDERS, 91, S84 - S84
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Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function
Journal article
Allan L. et al, (2006), Combinatorial Chemistry & High Throughput Screening, 9, 9 - 14
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Fe65 and X11β co-localize with and compete for binding to the amyloid precursor protein
Journal article
Lau K-F. et al, (2000), NeuroReport, 11, 3607 - 3610
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Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease
Journal article
McLoughlin DM. et al, (1999), European Journal of Neuroscience, 11, 1988 - 1994
Nicholas Irving
Ph.D
Translational Neuroscience Research Portfolio Manager
I’m responsible for promoting translational opportunities across all areas of Oxford Neuroscience from basic science to experimental medicine. Due to my background, I work closely with the MSD Business Development Office in facilitating interactions with industry. I also organise the strategic neuroscience management committees within the University. I look after a number of our international collaborations. I am actively involved in public engagement and coordinate Brain Awareness Week activities across Oxford.
Prior to joining the University, I worked for over ten years in the pharmaceutical industry where I gained extensive experience in project and portfolio management for CNS disorders. I studied for my Ph.D. with John Hardy at St Mary’s Hospital Medical School in London and have held postdoctoral positions at Johns Hopkins University, with Roger Reeves, and the Institute of Psychiatry, with Simon Lovestone. My academic research focussed on the molecular and cellular biology of neurodegenerative diseases including Alzheimer’s disease.
Key publications
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A mouse model for Down syndrome exhibits learning and behaviour deficits
Journal article
Reeves RH. et al, (1995), Nature Genetics, 11, 177 - 184
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Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
Journal article
Goate A. et al, (1991), Nature, 349, 704 - 706
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Mouse chromosome-specific markers generated by PCR and their mapping through interspecific backcrosses
Journal article
Irving NG. and Brown SDM., (1991), Genomics, 11, 679 - 686
Recent publications
-
The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists
Journal article
Napier S. et al, (2011), Bioorganic & Medicinal Chemistry Letters, 21, 3163 - 3167
-
Investigating the potential role of oestrogen receptor beta (ER Beta) in affective disorders
Journal article
Irving NG. et al, (2006), JOURNAL OF AFFECTIVE DISORDERS, 91, S84 - S84
-
Development of a Novel High-Throughput Assay for the Investigation of GlyT-1b Neurotransmitter Transporter Function
Journal article
Allan L. et al, (2006), Combinatorial Chemistry & High Throughput Screening, 9, 9 - 14
-
Fe65 and X11β co-localize with and compete for binding to the amyloid precursor protein
Journal article
Lau K-F. et al, (2000), NeuroReport, 11, 3607 - 3610
-
Mint2/X11-like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease
Journal article
McLoughlin DM. et al, (1999), European Journal of Neuroscience, 11, 1988 - 1994