Research groups
Dr Sophie Binks
Clinical Lecturer
Honorary Neurology SpR
Brief biography
I am a clinical lecturer and honorary neurology registrar in Oxford recently awarded a DPhil in autoimmune neurology, and now establishing myself as a clinician-scientist. My DPhil supervisors and current collaborators are Prof Sarosh Irani, as well as Prof Julian Knight and Dr Kate Elliott from the Knight Group, Wellcome Centre for Human Genetics, Oxford.
My research focuses on clinical and genetic aspects of autoimmune encephalitides. Previously (2016-2017) I was an Academic Clinical Fellow in Neurology in Oxford investigating clinical and HLA associations of LGI1- and CASPR2-antibody encephalitis, and prior to that I completed an Academic Foundation Programme in Neurology in Brighton.
Key publications
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Residual Fatigue and Cognitive Deficits in Patients After Leucine-Rich Glioma-Inactivated 1 Antibody Encephalitis.
Journal article
Binks SNM. et al, (2021), JAMA Neurol, 78, 617 - 619
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Distinct HLA associations of LGI1 and CASPR2-antibody diseases
Journal article
Binks S. et al, (2018), Brain, 141, 2263 - 2271
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LGI1, CASPR2 and related antibodies: a molecular evolution of the phenotypes
Journal article
Binks SNM. et al, (2018), Journal of Neurology, Neurosurgery & Psychiatry, 89, 526 - 534
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Effect of high-dose simvastatin on cognitive, neuropsychiatric, and health-related quality-of-life measures in secondary progressive multiple sclerosis: secondary analyses from the MS-STAT randomised, placebo-controlled trial.
Journal article
Chan D. et al, (2017), Lancet Neurol, 16, 591 - 600
Recent publications
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Parallel roles of neuroinflammation in feline and human epilepsies.
Journal article
Binks S. et al, (2022), Vet J
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Human Leukocyte Antigen Association Study Reveals DRB1*04:02 Effects Additional to DRB1*07:01 in Anti-LGI1 Encephalitis
Journal article
Peris Sempere V. et al, (2022), Neurology - Neuroimmunology Neuroinflammation, 9, e1140 - e1140
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Autoimmune encephalitis: clinical spectrum and management.
Journal article
Uy CE. et al, (2021), Pract Neurol, 21, 412 - 423
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Leucine‐Rich Glioma‐Inactivated 1 versus Contactin‐Associated Protein‐like 2 Antibody Neuropathic Pain: Clinical and Biological Comparisons
Journal article
Ramanathan S. et al, (2021), Annals of Neurology, 90, 683 - 690
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Paraneoplastic neurological syndromes: a practical approach to diagnosis and management.
Journal article
Binks S. et al, (2021), Pract Neurol