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Studies of changes in cerebral neocortical thickness often rely on small control samples for comparison with specific populations with abnormal visual systems. We present a normative dataset for FreeSurfer-derived cortical thickness across 25 human visual areas derived from 960 participants in the Human Connectome Project. Cortical thickness varies systematically across visual areas, in broad agreement with canonical visual system hierarchies in the dorsal and ventral pathways. In addition, cortical thickness estimates show consistent within-subject variability and reliability. Importantly, cortical thickness estimates in visual areas are well described by a normal distribution, making them amenable to direct statistical comparison.

Original publication

DOI

10.1016/j.neuroimage.2019.116057

Type

Journal article

Journal

Neuroimage

Publication Date

01/11/2019

Volume

201

Keywords

Cortical thickness, Extrastriate, FreeSurfer, Human connectome project, MRI, V1, Visual cortex, Adult, Cerebral Cortex, Female, Humans, Magnetic Resonance Imaging, Male, Organ Size, Reference Values, Visual Cortex, Young Adult