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Periodontitis is an infectious polymicrobial, immuno-inflammatory disease of multifactorial aetiology that has an impact on the health, production and welfare of ruminants. The objective of the present study was to determine the microbial profiles present in the gingival sulcus of cattle considered periodontally healthy and in the periodontal pocket of animals with periodontitis lesions using high-throughput bacterial 16S rRNA gene sequencing. Subgingival biofilm samples were collected from 40 cattle with periodontitis and 38 periodontally healthy animals. In total, 1923 OTUs were identified and classified into 395 genera or higher taxa. Microbial profiles in health differed significantly from periodontitis in their composition (p 

Original publication




Journal article


Vet Microbiol

Publication Date





1 - 6


Bacteria, Cattle, High-throughput sequencing, Microbiome, Periodontal disease, Animals, Bacteria, Biofilms, Cattle, Computational Biology, Dental Plaque, Dysbiosis, Gingiva, High-Throughput Nucleotide Sequencing, Microbiota, Oral Health, Periodontitis, RNA, Ribosomal, 16S