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Retinopathy is a well-recognized toxic effect of hydroxychloroquine treatment. As hydroxychloroquine retinopathy is potentially a vision-threatening condition, early detection is imperative to minimize vision loss due to drug toxicity. However, early detection of hydroxychloroquine retinopathy is still challenging even with modern retinal imaging techniques. No treatment has been established for this condition, except for drug cessation to minimize further damage. In this perspective article, we aimed to summarize the knowledge gaps and unmet needs in current clinical practice and research in hydroxychloroquine retinopathy. The information presented in this article may help guide the future directions of screening practices and research in hydroxychloroquine retinopathy.

Original publication

DOI

10.3389/fmed.2023.1196815

Type

Journal article

Journal

Front Med (Lausanne)

Publication Date

2023

Volume

10

Keywords

definition, hydroxychloroquine, natural history, perspectives, retinal toxicity, screening, unmet needs