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Myasthenia gravis and myasthenic syndromes are diseases of the neuromuscular junction. Autoantibodies and toxins to or mutations in one of the synaptic proteins are the main causes of dysfunction. Myasthenic phenotypes can be classified according to the basic aetiological mechanisms or divided depending on the clinical phenotype.

Original publication

DOI

10.3109/08916931003602130

Type

Journal article

Journal

Autoimmunity

Publication Date

08/2010

Volume

43

Pages

344 - 352

Keywords

Adult, Aged, Autoantibodies, Female, Humans, Infant, Newborn, Lambert-Eaton Myasthenic Syndrome, Male, Middle Aged, Muscle Weakness, Muscles, Mutation, Myasthenia Gravis, Myasthenic Syndromes, Congenital, Neuromuscular Junction, Receptor Protein-Tyrosine Kinases, Receptors, Cholinergic, Synaptic Transmission