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The pathogenesis of multiple sclerosis (MS) remains unknown. Although inflammation, demyelination and axonal injury are all involved, the primary pathogenic process is not clear. In this paper we challenge the hypothesis that MS is a primary inflammatory condition, and suggest that axonal damage may occur independently.

Original publication

DOI

10.1191/1352458504ms1019rr

Type

Journal article

Journal

Mult Scler

Publication Date

06/2004

Volume

10

Pages

326 - 329

Keywords

Axons, Humans, Multiple Sclerosis, Neuritis