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Leber's hereditary optic neuropathy is a mitochondrial disorder causing bilateral optic nerve degeneration. It is sometimes associated with clinical signs of multiple sclerosis. We report MRI findings in two patients with LHON-MS and comment on possible distinguishing features of this disease entity.

Original publication

DOI

10.1111/j.1468-1331.2007.01757.x

Type

Journal article

Journal

Eur J Neurol

Publication Date

05/2007

Volume

14

Pages

591 - 593

Keywords

Adult, Brain, Diagnosis, Differential, Disease Progression, Early Diagnosis, Female, Gait Disorders, Neurologic, Humans, Magnetic Resonance Imaging, Middle Aged, Multiple Sclerosis, Nerve Fibers, Myelinated, Optic Atrophy, Hereditary, Leber, Optic Nerve, Predictive Value of Tests, Sensation Disorders, Vision, Low