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Utilizing a Mus spretus/Mus domesticus (C57BL/10) interspecific backcross, we have constructed a multipoint genetic map of mouse chromosome 16 that extends 43.2 cM from the proximal Prm-1 locus to the distal Ets-2 locus. The genetic map incorporates three new markers: D16Smh6, a random genomic clone; Pgk-1ps1, a phosphoglycerate kinase pseudogene; and the growth-associated protein Gap43. The map position of Gap43 indicates the presence, on mouse chromosome 16, of a significant-size conserved linkage group with human chromosome 3.

Type

Journal article

Journal

Genomics

Publication Date

02/1991

Volume

9

Pages

386 - 389

Keywords

Animals, Chromosome Mapping, Crosses, Genetic, GAP-43 Protein, Genetic Linkage, Genetic Markers, Humans, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Nerve Tissue Proteins, Phosphoglycerate Kinase, Polymorphism, Restriction Fragment Length, Pseudogenes