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The gene locus for the alpha 2 chain of type 1 collagen (Cola-2) was previously assigned to chromosome 16. Here we demonstrate, utilising both somatic cell hybrid analysis and genetic linkage analysis, in an interspecific Mus domesticus x Mus spretus cross that Cola-2 fails to cosegregate with mouse chromosome 16, but is linked to the Met proto-oncogene on chromosome 6.


Journal article


Cytogenet Cell Genet

Publication Date





121 - 122


Animals, Chromosome Mapping, Collagen, Cricetinae, Cricetulus, Crosses, Genetic, Female, Hybrid Cells, Male, Mice, Nucleic Acid Hybridization, Proto-Oncogenes