Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

<jats:title>Abstract</jats:title><jats:p>This study used real-time fMRI-based neurofeedback (NF) to modulate functional connectivity patterns in the emotional regulation networks in a sample of adolescent girls. Adolescence is a developmental period which brings along changes at multiple levels, such as hormonal changes, improvements in socio-emotional processing, as well as ongoing brain maturation and functioning. It has been suggested that these changes increase the risk for the individual. For example, early, difficulties with emotion regulation have been linked to a range of mental health problems, such as anxiety. Here we successfully trained participants to modulate the functional coupling of the prefrontal cortex and the amygdala towards a more negative connectivity pattern, which resembles the connectivity pattern found in the mature brain. These brain-based changes were related to changes at the behavioural level. We also found that the modulation largely depends on the specific neurofeedback implementation, which provides important insights for future NF training approaches.</jats:p>

Original publication




Journal article


Cold Spring Harbor Laboratory

Publication Date