Prion Protein Endoproteolysis: Cleavage Sites, Mechanisms and Connections to Prion Disease
Castle AR. and Westaway D., (2025), Journal of Neurochemistry, 169
Monitoring α-synuclein ubiquitination dynamics reveals key endosomal effectors mediating its trafficking and degradation
Zenko D. et al, (2023), Science Advances, 9
Beta-endoproteolysis of the cellular prion protein by dipeptidyl peptidase-4 and fibroblast activation protein
Castle AR. et al, (2023), Proceedings of the National Academy of Sciences, 120
Investigating CRISPR/Cas9 gene drive for production of disease-preventing prion gene alleles
Castle AR. et al, (2022), PLOS ONE, 17, e0269342 - e0269342
Susceptibility of Beavers to Chronic Wasting Disease
Herbst A. et al, (2022), Biology, 11, 667 - 667
Prion protein with a mutant N-terminal octarepeat region undergoes cobalamin-dependent assembly into high–molecular weight complexes
Daude N. et al, (2022), Journal of Biological Chemistry, 298, 101770 - 101770
Application of high-throughput, capillary-based Western analysis to modulated cleavage of the cellular prion protein
Castle AR. et al, (2019), Journal of Biological Chemistry, 294, 2642 - 5291
The cellular and pathologic prion protein
Gill AC. and Castle AR., (2018), Human Prion Diseases, 21 - 44
Physiological Functions of the Cellular Prion Protein
Castle AR. and Gill AC., (2017), Frontiers in Molecular Biosciences, 4