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C9orf72-ALS human iPSC microglia are pro-inflammatory and toxic to co-cultured motor neurons via MMP9
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Vahsen BF. et al, (2023), Nature Communications, 14
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
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Human stem cell models of neurodegeneration: From basic science of amyotrophic lateral sclerosis to clinical translation
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Non-neuronal cells in amyotrophic lateral sclerosis — from pathogenesis to biomarkers
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Vahsen BF. et al, (2021), Nature Reviews Neurology, 17, 333 - 348
AAV-mediated inhibition of ULK1 promotes axonal regeneration in the central nervous system in vitro and in vivo
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Ribas VT. et al, (2021), Cell Death & Disease, 12
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
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Klionsky DJ. et al, (2021), Autophagy, 17, 1 - 382
ULK1 as a novel therapeutic target in neurodegeneration
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Lingor P. and Vahsen B., (2021), Neural Regeneration Research, 16, 1212 - 1212
Inhibition of the autophagic protein ULK1 attenuates axonal degeneration in vitro and in vivo, enhances translation, and modulates splicing
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Vahsen BF. et al, (2020), Cell Death & Differentiation, 27, 2810 - 2827
AAV-Mediated Expression of Dominant-Negative ULK1 Increases Neuronal Survival and Enhances Motor Performance in the MPTP Mouse Model of Parkinson’s Disease
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