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Publications

Initiation and progression of α-synuclein pathology in Parkinson’s disease

Tofaris GK., (2022), Cellular and Molecular Life Sciences, 79

Longitudinal changes of early motor and cognitive symptoms in progressive supranuclear palsy: the OxQUIP study

Pereira MF. et al, (2022), BMJ Neurology Open, 4, e000214 - e000214

Phenotypic manifestation of α-synuclein strains derived from Parkinson’s disease and multiple system atrophy in human dopaminergic neurons

Tanudjojo B. et al, (2021), Nature Communications, 12

Validation of α-synuclein in L1CAM-immunocaptured exosomes as a biomarker for the stratification of Parkinsonian syndromes

TOFARIS G., (2021), Movement Disorders

Facile impedimetric analysis of neuronal exosome markers in Parkinson's disease diagnostics

FU Y. et al, (2020), Analytical Chemistry

Serum neuronal exosomes predict and differentiate Parkinson’s disease from atypical parkinsonism

Jiang C. et al, (2020), Journal of Neurology, Neurosurgery & Psychiatry, 91, 720 - 729

How is alpha-synuclein cleared from the cell?

(2019), Journal of Neurochemistry

Monitoring α-synuclein proteotoxicity in Drosophila models

Szabo A. and Tofaris G., (2019), Methods in Molecular Biology, 1948, 199 - 208

Convergent molecular defects underpin diverse neurodegenerative diseases

Tofaris GK. and Buckley NJ., (2018), Journal of Neurology, Neurosurgery & Psychiatry, 89, 962 - 969

Stem cell modeling of mitochondrial parkinsonism reveals key functions of OPA1

Jonikas M. et al, (2018), Annals of Neurology, 83, 915 - 925

A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson’s Disease

Tofaris GK., (2017), Journal of Parkinson's Disease, 7, 569 - 576

A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson's Disease.

Tofaris G., (2017), npj Parkinson's Disease

The Transcellular Propagation and Intracellular Trafficking of α-Synuclein

Tofaris GK. et al, (2017), Cold Spring Harbor Perspectives in Medicine, 7, a024380 - a024380

Identification of Usp8 as a toxicity modifying Deubiquitinase for alpha-synuclein

Alexopoulou Z. et al, (2017), EUROPEAN JOURNAL OF NEUROLOGY, 24, 766 - 766

Concentration-Normalized Electroanalytical Assaying of Exosomal Markers

Li Q. et al, (2017), Analytical Chemistry, 89, 3184 - 3190

PUPILLARY REWARD SENSITIVITY IS A MARKER OF APATHY IN PARKINSON'S DISEASE

Muhammed K. et al, (2016), Journal of Neurology, Neurosurgery & Psychiatry, 87, e1.146 - e1

Reward sensitivity deficits modulated by dopamine are associated with apathy in Parkinson’s disease

Muhammed K. et al, (2016), Brain, 139, 2706 - 2721

Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease

Alexopoulou Z. et al, (2016), Proceedings of the National Academy of Sciences, 113, E4688 - E4697

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

Fernandes HJR. et al, (2016), Stem Cell Reports, 6, 342 - 356

Intact Acquisition and Short-Term Retention of Non-Motor Procedural Learning in Parkinson’s Disease

Panouillères MTN. et al, (2016), PLOS ONE, 11, e0149224 - e0149224

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