Sonic hedgehog medulloblastoma cells in co-culture with cerebellar organoids converge towards in vivo malignant cell states
JACOB J., (2025), Neuro-Oncology Advances
Sonic hedgehog medulloblastoma cells in co-culture with cerebellar organoids converge towards in vivo malignant cell states
van Essen MJ. et al, (2024), Neuro-Oncology Advances
PTCH1-mutant human cerebellar organoids exhibit altered neural development and recapitulate early medulloblastoma tumorigenesis
van Essen MJ. et al, (2024), Disease Models & Mechanisms, 17
Messenger RNA brings gene editing a step closer to treat muscular dystrophies.
Jacob J., (2022), Mol Ther Nucleic Acids, 28, 462 - 463
Augmented Reality Can Improve Accuracy in Identifying Botulinum Toxin Injection Sites
MUHAMMED K., (2022), EMJ Innovations
CRISPR-Cas Gene Perturbation and Editing in Human Induced Pluripotent Stem Cells.
van Essen M. et al, (2021), CRISPR J
Deconstructing cerebellar development cell by cell
van Essen MJ. et al, (2020), PLOS Genetics, 16, e1008630 - e1008630
Ptosis that resolves with application of an ice pack
Chakraborty A. and Jacob J., (2020), BMJ, m1147 - m1147
Evaluating a Personal Information Pack for Patients with Epilepsy
Edmond E. et al, (2018), EPILEPSIA, 59, S140 - S141
Focal precentral gyrus involvement in osmotic demyelination
Turner MR. et al, (2017), Practical Neurology, 17, 410 - 411
Reduced cholesterol levels impair Smoothened activation in Smith–Lemli–Opitz syndrome
Blassberg R. et al, (2016), Human Molecular Genetics, 25, 693 - 705
Cortical interneuron dysfunction in epilepsy associated with autism spectrum disorders
Jacob J., (2016), Epilepsia, 57, 182 - 193
THE LINK BETWEEN CHOLESTEROL AND HEDGEHOG SIGNALLING IN EPILEPSY AND AUTISM SPECTRUM DISORDER: A CELLULAR MODEL OF SMITH-LEMLI-OPITZ SYNDROME
Jacob J. and Blassberg R., (2015), EPILEPSIA, 56, 120 - 120
Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1
Jacob J. et al, (2013), Current Biology, 23, 412 - 418
Valproic Acid silencing ofascl1b/ascl1results in the failure of serotonergic differentiation in a zebrafish model of Fetal Valproate Syndrome
Jacob J. et al, (2013), Disease Models & Mechanisms
Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain
Jacob J. et al, (2009), Development, 136, 2477 - 2485
Temporal control of neuronal diversity: common regulatory principles in insects and vertebrates?
Jacob J. et al, (2008), Development, 135, 3481 - 3489