Advantages of routine next generation sequencing over standard genetic testing in the ALS clinic.
Journal article
Scaber J. et al, (2023), Eur J Neurol
Human iPSC co-culture model to investigate the interaction between microglia and motor neurons
Journal article
Vahsen BF. et al, (2022), Scientific Reports, 12
A case of SOD1 deficiency: implications for clinical trials.
Journal article
Farrimond L. and Talbot K., (2022), Brain
Multicentre appraisal of amyotrophic lateral sclerosis biofluid biomarkers shows primacy of blood neurofilament light chain
Journal article
Thompson AG. et al, (2022), Brain Communications, 4
Impairment of mitochondrial calcium buffering links mutations in C9orf72 and TARDBP in iPS-derived motor neurons from patients with ALS/FTD
Journal article
DAFINCA R. et al, (2020), Stem Cell Reports
Single-copy expression of an amyotrophic lateral sclerosis-linked TDP-43 mutation (M337V) in BAC transgenic mice leads to altered stress granule dynamics and progressive motor dysfunction
Journal article
Gordon D. et al, (2019), Neurobiology of Disease, 121, 148 - 162
Initial Identification of a Blood-Based Chromosome Conformation Signature for Aiding in the Diagnosis of Amyotrophic Lateral Sclerosis
Journal article
Salter M. et al, (2018), EBioMedicine, 33, 169 - 184
TARDBP pathogenic mutations increase cytoplasmic translocation of TDP-43 and cause reduction of endoplasmic reticulum Ca2+ signaling in motor neurons
Journal article
Mutihac R. et al, (2015), Neurobiology of Disease, 75, 64 - 77
Memantine and cholinesterase inhibitor combination therapy for Alzheimer's disease: a systematic review
Journal article
Farrimond LE. et al, (2012), BMJ Open, 2, e000917 - e000917