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Publications

Envisioning the development of a CRISPR-Cas mediated base editing strategy for a patient with a novel pathogenic CRB1 single nucleotide variant.

Bellingrath J-S. et al, (2022), Ophthalmic Genet, 1 - 10

Characterizing Visual Fields in RPGR Related Retinitis Pigmentosa Using Octopus Static-Automated Perimetry

Buckley TMW. et al, (2022), Translational vision science & technology, 11

EFFICACY OF HALF-DOSE PHOTODYNAMIC THERAPY VERSUS HIGH-DENSITY SUBTHRESHOLD MICROPULSE LASER FOR TREATING PIGMENT EPITHELIAL DETACHMENTS IN CHRONIC CENTRAL SEROUS CHORIORETINOPATHY.

Feenstra HMA. et al, (2022), Retina (Philadelphia, Pa.), 42, 721 - 729

Tropism of AAV Vectors in Photoreceptor-Like Cells of Human iPSC-Derived Retinal Organoids.

McClements ME. et al, (2022), Transl Vis Sci Technol, 11

Bioengineering strategies for restoring vision.

Cehajic-Kapetanovic J. et al, (2022), Nat Biomed Eng

Outer retinal and choriocapillaris modifications in choroideremia: three differentially impaired retinal regions and the potential diagnostic role of the external limiting membrane.

Arrigo A. et al, (2022), Eye (London, England)

The Scope of Pathogenic ABCA4 Mutations Targetable by CRISPR DNA Base Editing Systems—A Systematic Review

Piotter E. et al, (2022), Frontiers in Genetics, 12

Gene therapy and treatment trials

MacLaren RE. and Cehajic-Kapetanovic J., (2022), Clinical Ophthalmic Genetics and Genomics, 63 - 66

Rapid Quantification of the Binocular Visual Field for Clinical Trials: Performance of a Modified Esterman Supra-Threshold Test Implemented with the Open Perimetry Interface.

Andrews CD. et al, (2022), Clin Ophthalmol, 16, 1513 - 1523

Retinal cadherins and the retinal cadherinopathies: current concepts and future directions

YUSUF I. et al, (2021), Progress in Retinal and Eye Research

Mirtron-mediated RNA knockdown/replacement therapy for the treatment of dominant retinitis pigmentosa

Orlans HO. et al, (2021), Nature Communications, 12

In Silico Analysis of Pathogenic CRB1 Single Nucleotide Variants and Their Amenability to Base Editing as a Potential Lead for Therapeutic Intervention.

Bellingrath J-S. et al, (2021), Genes (Basel), 12

First-In-Human Robot-Assisted Subretinal Drug Delivery Under Local Anaesthesia A Randomised Clinical Trial.

Cehajic-Kapetanovic J. et al, (2021), Am J Ophthalmol

Structural and Functional Characteristics of Color Vision Changes in Choroideremia

Jolly JK. et al, (2021), Frontiers in Neuroscience, 15, 1287 - 1287

CRISPR Systems Suitable for Single AAV Vector Delivery.

Stevanovic M. et al, (2021), Curr Gene Ther

Endpoints for Measuring Efficacy in Clinical Trials for Inherited Retinal Disease.

Chung DC. et al, (2021), International ophthalmology clinics, 61, 63 - 78

RESPONSE OF CHOROIDAL ABNORMALITIES TO PHOTODYNAMIC THERAPY VERSUS MICROPULSE LASER IN CHRONIC CENTRAL SEROUS CHORIORETINOPATHY: Place Trial Report No. 4.

van Rijssen TJ. et al, (2021), Retina, 41, 2122 - 2131

Characterizing the cellular immune response to subretinal AAV gene therapy in the murine retina

Chandler LC. et al, (2021), Molecular Therapy - Methods & Clinical Development, 22, 52 - 65

Therapy Approaches for Stargardt Disease

Piotter E. et al, (2021), Biomolecules, 11, 1179 - 1179

Insights on the Regeneration Potential of Müller Glia in the Mammalian Retina

Salman A. et al, (2021), Cells, 10, 1957 - 1957

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