In vivo calcium imaging reveals directional sensitivity of C‐low threshold mechanoreceptors
Semizoglou E. et al, (2025), The Journal of Physiology
Identification of SLC45A4 as a pain gene encoding a neuronal polyamine transporter.
Middleton SJ. et al, (2024)
A humanized chemogenetic system inhibits murine pain-related behavior and hyperactivity in human sensory neurons
Perez-Sanchez J. et al, (2023), Science Translational Medicine, 15
GluCl.CreON enables selective inhibition of molecularly defined pain circuits
Middleton SJ. et al, (2023), Pain, Publish Ahead of Print
Sodium-calcium exchanger-3 regulates pain “wind-up”: From human psychophysics to spinal mechanisms
Trendafilova T. et al, (2022), Neuron, 110, 2571 - 2587.e13
Nav1.7 is required for normal C-low threshold mechanoreceptor function in humans and mice
Middleton SJ. et al, (2021), Brain
The structure of sensory afferent compartments in health and disease
Middleton SJ. et al, (2021), Journal of Anatomy
Studying human nociceptors: from fundamentals to clinic
Middleton SJ. et al, (2021), Brain, 144, 1312 - 1335
Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
Dawes JM. et al, (2018), Neuron, 97, 806 - 822.e10
Congenital deafness is associated with specific somatosensory deficits in adolescents
Moshourab R. et al, (2017), Scientific Reports, 7
Using an engineered glutamate-gated chloride channel to silence sensory neurons and treat neuropathic pain at the source
Weir GA. et al, (2017), Brain, 140, 2570 - 2585