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Publications

Aneuploidy effects on human gene expression across three cell types.

Liu S. et al, (2023), Proc Natl Acad Sci U S A, 120

A novel human iPSC model of COL4A1/A2 small vessel disease unveils a key pathogenic role of matrix metalloproteinases in extracellular matrix abnormalities

Al-Thani M. et al, (2023)

Mathematical modelling of brain mTOR activity identifies selective vulnerability of cell types and signalling pathways

Pokhilko A. et al, (2022)

Lipopolysaccharide distinctively alters human microglia transcriptomes to resemble microglia from Alzheimer's disease mouse models.

Monzón-Sandoval J. et al, (2022), Dis Model Mech, 15

Neurons derived from individual early Alzheimer's disease patients reflect their clinical vulnerability.

Ng B. et al, (2022), Brain Commun, 4

Global proteomic analysis of extracellular matrix in mouse and human brain highlights relevance to cerebrovascular disease.

Pokhilko A. et al, (2021), J Cereb Blood Flow Metab, 41, 2423 - 2438

Targeted single-cell RNA sequencing of transcription factors enhances the identification of cell types and trajectories

Pokhilko A. et al, (2021), Genome Research

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses

CADER M. et al, (2020), Nature Communications

Common transcriptional signatures of neuropathic pain

Pokhilko A. et al, (2020), Pain, 161, 1542 - 1554

Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

Curion F. et al, (2020), RNA Biology, 1 - 13

Patient fibroblast circadian rhythms predict lithium sensitivity in bipolar disorder

Sanghani HR. et al, (2020), Molecular Psychiatry

The genetics of migraine and the path to precision medicine.

Cader MZ., (2020), 255, 403 - 418

A causal role for TRESK loss of function in migraine mechanisms.

Pettingill P. et al, (2019), Brain, 142, 3852 - 3867

High glucose concentrations mask cellular phenotypes in a stem cell model of tuberous sclerosis complex.

Rocktäschel P. et al, (2019), Epilepsy Behav, 101

IHC 2019 Author index

O'connor E. et al, (2019), CEPHALALGIA, 39, 1 - 1

Using longitudinal real-world electronic healthcare records to study long-term outcomes in headache sufferers.

Nash A. et al, (2019), CEPHALALGIA, 39, 43 - 43

The Role of TRESK in Discrete Sensory Neuron Populations and Somatosensory Processing

CADER M. et al, (2019), Frontiers in Molecular Neuroscience

Proteolytic shedding of the prion protein via activation of metallopeptidase ADAM10 reduces cellular binding and toxicity of amyloid-β oligomers.

Jarosz-Griffiths HH. et al, (2019), The Journal of biological chemistry, 294, 7085 - 7097

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease.

Fang EF. et al, (2019), Nat Neurosci, 22, 401 - 412

Culprit or Bystander: Defective Mitophagy in Alzheimer's Disease.

Xie C. et al, (2019), Front Cell Dev Biol, 7

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