Contact information
Ahmed Salman
Postdoctoral Research Scientist
Ahmed's background is in molecular cell biology and transgenic animal models for disease, specifically retinal disease. After completing his BSc (Honours) in Genetics at the University of Glasgow, Ahmed joined Sir William Dunn School of Pathology at the University of Oxford in 2009 and completed his MSc by research in mouse embryonic development in 2013 where he gained his experience in transgenic animal models. He later joined the Welcome Trust Centre for Human Genetics (currently Welcome Centre for Human Genetics) at the University of Oxford working on DNA double-stranded break repair mechanisms before starting his PhD in developing a transgenic murine model for Nystagmus, a significant eye disease with uncontrolled eye movements at the University of Southampton in 2014.
Ahmed joined Professor MacLaren's group in 2019 working on characterising preclinical models for gene therapy using a variety of viral and non-viral delivery approaches of gene editing technologies such as CRISPR.
Research groups
Collaborators
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Robert MacLaren
Professor of Ophthalmology
Recent publications
CRISPR targeting of SNPs associated with age-related macular degeneration in ARPE-19 cells: a potential model for manipulating the complement system
Journal article
Salman A. et al, (2025), Gene Therapy, 32, 132 - 141
Comparison of CRISPR-Cas13b RNA base editing approaches for USH2A-associated inherited retinal degeneration
Journal article
Fry LE. et al, (2025), Communications Biology, 8
Spontaneously Immortalised Nonhuman Primate Müller Glia Cell Lines as Source to Explore Retinal Reprogramming Mechanisms for Cell Therapies
Journal article
Salman A. et al, (2025), Journal of Cellular Physiology, 240
Rescue of cone and rod photoreceptor function in a CDHR1-model of age-related retinal degeneration
Journal article
Yusuf IH. et al, (2024), Molecular Therapy, 32, 1445 - 1460