Cookies on this website

We use cookies to ensure that we give you the best experience on our website. If you click 'Accept all cookies' we'll assume that you are happy to receive all cookies and you won't see this message again. If you click 'Reject all non-essential cookies' only necessary cookies providing core functionality such as security, network management, and accessibility will be enabled. Click 'Find out more' for information on how to change your cookie settings.

Accept all cookies Reject all non-essential cookies Find out more

Ana Aragon-Gonzalez

Ana Aragon-Gonzalez

Ana Aragón-González

iPSC-based modelling of Parkinson's Disease

As a post-doctoral researcher, my focus is on studying the cellular and molecular mechanisms of neurodegeneration and dementia. Previously, I conducted research on the dynamics of the Blood-Brain Barrier (BBB) in the context of Motor Neuron Disease.

Currently, at the University of Oxford, I utilize CRISPR to deactivate genes in human i-PSCs-derived Dopaminergic Neurons. In our lab, we investigate the cellular trafficking and aggregation of α-synuclein. To identify modifiers of its turnover and aggregation related to our target genes, I employ various biochemical and microscopy techniques.

I hope my work on Parkinsons’ genetic features can ultimately benefit patients.