Contact information
Research groups
Anna Li
DPhil Student
I am a second year OXION DPhil student co-supervised by Dr Yin Dong from NDCN and Associate Professor Alex Bullock from CMD. I am interested in studying the structures and functions of the muscle-type nicotinic acetylcholine receptor (AChR) as well as the SLC1A family of amino acid transporters - both of which are membrane proteins implicated in neurological disorders. I am currently working on protein expression and purification with a goal to solve their 3D structures using Cryo-EM.
Previously, I completed my Bachelor of Biomedicine with Honours at the University of Melbourne, Australia. During my research year at the Florey Institute of Neuroscience and Mental Health, I characterised a pathogenic mutation in Cav2.1 associated with epileptic encephalopathy.
Recent publications
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EAAT3 modulation: A potential novel avenue towards remyelination in multiple sclerosis
Journal article
van Veggel L. et al, (2025), Biomedicine & Pharmacotherapy, 186, 117960 - 117960
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Structures of the human adult muscle-type nicotinic receptor in resting and desensitized states
Journal article
Li A. et al, (2025), Cell Reports, 44, 115581 - 115581
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Structures of the human adult muscle-type nicotinic receptor in resting and desensitised states
Preprint
Li A. et al, (2024)
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Still in Search for an EAAT Activator: GT949 Does Not Activate EAAT2, nor EAAT3 in Impedance and Radioligand Uptake Assays
Journal article
van Veggel L. et al, (2024), ACS Chemical Neuroscience, 15, 1424 - 1431
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High-Throughput Expression and Purification of Human Solute Carriers for Structural and Biochemical Studies
Journal article
Raturi S. et al, (2023), Journal of Visualized Experiments