Charalampos (Harris) Sotirakis
PhD
Academic visitor/ Researcher in biomarkers for Parkinson’s disease
Identification of biomarkers for parkinsonian disorders.
My motivation
Movement disorders such as Parkinson's disease (PD) and Progressive Supranuclear Palsy (PSP) are neurodegenerative conditions that significantly reduce the quality of life for those affected.
My research focuses on exploring the potential of wearable sensors and data science, such as machine learning applications, to develop robust digital biomarkers that accurately detect motor symptoms and monitor the disease progression promptly. Such biomarkers can be used by clinical experts to improve diagnostic accuracy, monitor the disease progression and personalise disease management plans.
Our research within the NeuroMetrology group demonstrates that in both PD and PSP our digital biomarkers are able to detect the disease progression earlier than the traditional clinical examinations. This is important because capturing early signs of PD motor symptom progression can enable the assessment of the effectiveness of medical treatment.
Recent publications
Comparative analysis of trunk sensor placement in people with and without Parkinson’s disease
Journal article
Sotirakis C. et al, (2025), Journal of Biomechanics, 192, 112975 - 112975
Verbal fluency is associated with Gait impairment in Progressive Supranuclear Palsy
Journal article
D’Souza A. et al, (2025), Clinical Parkinsonism & Related Disorders, 13, 100380 - 100380
EduGenZ: A Gamified Educational Framework for GenZ Using Affective and Immersive Technology
Conference paper
Hadjileontiadou SJ. et al, (2025), Communications in Computer and Information Science, 2479 CCIS, 292 - 307
Predicting future fallers in Parkinson’s disease using kinematic data over a period of 5 years
Journal article
Sotirakis C. et al, (2024), npj Digital Medicine, 7
Goalkeepers' plasticity during learning of a whole-body visuomotor rotation in a stable or variable environment.
Journal article
Vouras I. et al, (2023), Eur J Sport Sci, 23, 2148 - 2156