Art and Neuroscience
2019 : I have been awarded a Public Engagement with Research Seed fund grant for our project ‘Picturing Parkinsons’. Our first project event is this Saturday March 16th at the Ashmolean museum Picturing Parkinson's : building bridges between neuroscientists and patients.
Awarded the The Vice-Chancellor’s Awards for Public Engagement with Research
We might think that we can see everything that is happening around us, and it is often said that ‘seeing is believing’, indicating that visual perception is considered one of the most trustworthy means of obtaining information about what is happening around us. However, research has revealed that perception does not capture as much information about the world as we would think .
My interests lie in examining the neurobiological relationship between visual perception and art.
Please visit this website for more information https://www.ndcn.ox.ac.uk/public-engagement/art-and-neuroscience-project
- Principal Investigator
- Lecturer in Medicine at Brasenose College
A number of brain diseases affect various types of bodily movements, either producing unwanted movements such as tremors or reducing movement by making the patient stiff and slow, or sometimes both. One such condition is Parkinson’s disease which is where my research interests lie.
In my research clinics, I use a variety of quantitative experimental methods, based on precise measurement of subtle abnormalities of the speed and coordination of various movements such as saccades (fast eye movements) and hand movements.
There are two main strands to my work:
(a) Investigation of patients with very early stage Parkinson’s disease. The aim is to develop easy to apply and relatively cheap neurophysiological tests to aid more accurate diagnosis and monitoring of disease progression. These quantitative tests will also be used to monitor the response to new therapies in clinical trials.
(b) Investigation of the neurophysiological effects of, and mechanism underlying, Deep Brain Stimulation (DBS) in Parkinson’s disease. This is in collaboration with the Oxford Functional Neurosurgery Group.
More recently, I have started working with Professor Glyn Humphries and Dr Nele Demeyere, using a new tablet computer based system to test cognitive function in Parkinson’s patients.
Dementia and Neurodegenerative Research Network (DeNDRon)
I chair the Clinical Neurosciences Society
An internationally standardised antisaccade protocol.
Antoniades C. et al, (2013), Vision Res, 84, 1 - 5
Antisaccades and executive dysfunction in early drug-naive Parkinson's disease: The discovery study.
Antoniades CA. et al, (2015), Mov Disord, 30, 843 - 847
Deep brain stimulation: eye movements reveal anomalous effects of electrode placement and stimulation.
Antoniades CA. et al, (2012), PLoS One, 7
Deep brain stimulation of the globus pallidus interna improves performance in complex oculomotor tasks
Antoniades CA. et al, (2016), MOVEMENT DISORDERS, 31, S131 - S132
Using saccades as an early test of levodopa treatment in Parkinson's Disease
Lu ZJ. et al, (2018), MOVEMENT DISORDERS, 33, S468 - S469
Deep Brain Stimulation of the Subthalamic Nucleus Does Not Affect the Decrease of Decision Threshold during the Choice Process When There Is No Conflict, Time Pressure, or Reward.
Leimbach F. et al, (2018), J Cogn Neurosci, 30, 876 - 884
Art and Neuroscience
Antoniades CA., (2018)
Effects of Deep Brain Stimulation on Eye Movements and Vestibular Function.
Shaikh AG. et al, (2018), Front Neurol, 9
Quantifying Motor Impairment in Movement Disorders.
FitzGerald JJ. et al, (2018), Front Neurosci, 12