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Lara Fragapane
DPhil Student
I am a DPhil student at the Rosalind Franklin Institute, under the joint supervision of Dr Liang Wu, Dr Andrew Giltrap and Dr Yin Dong. My project utilises the expertise from the Dong group in combination with the cutting edge technologies available at the Franklin to help yield key structural and mechanistic insights of multi-glycosyltransferase complexes involved in the early N-glycosylation synthesis pathway and how they are implicated in Congenital Disorders of Glycosylation.
Previously, I graduated with a BSc in Biochemistry from the University of Bath, during which I conducted my professional placement year at the European Synchrotron Radiation Facility (ESRF) and the Institut Laue-Langevin (ILL), in Grenoble. Here, I utilised a range of structural and biophysical approaches, including X-ray crystallography, small-angle X-ray scattering and neutron reflectometry to study the therapeutic properties of the polyphenolic compounds, curcuminoid.