Collaborators
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David Bennett
Professor of Neurology and Neurobiology
Research groups
Colleges
Websites
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OXION
Ion Channels and Disease Initiative
Liam Peck
MA (Oxon) DPhil (Oxon)
Research Collaborator
Contact information
+44 (0)1865 234797
I completed my first 3 years of undergraduate pre-clinical medicine at Lady Margaret Hall, graduating with a BA (Hons) in Medical Sciences in 2015. During this time I undertook a Final Honours School research project on autoimmune-derived chronic pain, supervised by Prof David Bennett and Dr John Dawes of the Neural Injury Group in the NDCN. I was awarded the 2015 Martin Wronker Research Project Prize for my dissertation on CASPR2 autoimmunity and neuropathic pain.
I postponed my clinical studies to accept a 4-year Wellcome Trust Studentship on the Oxion DPhil in Ion Channels & Disease, at St John's College. In my first year I worked for Prof Anant Parekh (DPAG) researching slow inactivation of the store-operated calcium channel Orai1 via site-directed mutagenesis and calcium imaging of Orai1-transfected HEK cells.
This was followed by a second project with Prof Bennett studying the role of Kv1 channels in acute and neuropathic pain sensation, which became the subject of my DPhil thesis. This was conducted in collaboration with Prof Margarita Calvo (Universidad Católica, Santiago, Chile), my secondary DPhil supervisor Prof Anthony Dickenson (University College London) and Prof Andrew Todd (University of Glasgow).
I completed my DPhil in 2019 and subsequently returned to studying clinical medicine in Oxford.
As of 2017, I have been neuroscience tutor to undergraduate medical students at Lady Margaret Hall and, from 2020, I was appointed as a Non-Stipendiary Lecturer in Medicine at LMH.
Key publications
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Studying independent Kcna6 knock-out mice reveals toxicity of exogenous LacZ to central nociceptor terminals and differential effects of Kv1.6 on acute and neuropathic pain sensation
Journal article
Peck LJ. et al, (2021), The Journal of Neuroscience
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Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers.
Journal article
Lumley SF. et al, (2020), N Engl J Med
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Defining the Functional Role of NaV1.7 in Human Nociception
Journal article
McDermott LA. et al, (2019), Neuron, 101, 905 - 919.e8
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Immune or Genetic-Mediated Disruption of CASPR2 Causes Pain Hypersensitivity Due to Enhanced Primary Afferent Excitability
Journal article
Dawes JM. et al, (2018), Neuron, 97, 806 - 822.e10
Recent publications
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An Observational Cohort Study on the Incidence of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and B.1.1.7 Variant Infection in Healthcare Workers by Antibody and Vaccination Status
Journal article
Lumley SF. et al, (2022), Clinical Infectious Diseases, 74, 1208 - 1219
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Studying independent Kcna6 knock-out mice reveals toxicity of exogenous LacZ to central nociceptor terminals and differential effects of Kv1.6 on acute and neuropathic pain sensation
Journal article
Peck LJ. et al, (2021), The Journal of Neuroscience
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The Duration, Dynamics, and Determinants of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Antibody Responses in Individual Healthcare Workers
Journal article
Lumley SF. et al, (2021), Clinical Infectious Diseases, 73, e699 - e709
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COVID-19: Rapid antigen detection for SARS-CoV-2 by lateral flow assay: A national systematic evaluation of sensitivity and specificity for mass-testing
Working paper
Peto T. et al, (2021), EClinicalMedicine, 100924 - 100924
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Antibody Status and Incidence of SARS-CoV-2 Infection in Health Care Workers
Journal article
Lumley SF. et al, (2021), New England Journal of Medicine, 384, 533 - 540