OXION DPhil Student in Ion Channels and Disease
I completed my first 3 years of undergraduate pre-clinical medicine at Lady Margaret Hall, graduating with a BA (Hons) in Medical Sciences in 2015. During this time I undertook a Final Honours School research project on autoimmune-derived chronic pain, supervised by Prof David Bennett and Dr John Dawes of the Neural Injury Group in the NDCN. I was awarded the 2015 Martin Wronker Research Project Prize for my dissertation on CASPR2 autoimmunity and neuropathic pain.
I postponed my clinical studies to accept a 4-year Wellcome Trust Studentship on the Oxion DPhil in Ion Channels & Disease, at St John's College. In my first year I worked for Prof Anant Parekh (DPAG) researching slow inactivation of the store-operated calcium channel Orai1 via site-directed mutagenesis and calcium imaging of Orai1-transfected HEK cells.
This was followed by a second project with Prof Bennett studying the role of Kv1 channels in acute and neuropathic pain sensation, which has become the subject of my DPhil thesis. This has been conducted in collaboration with Prof Margarita Calvo (Universidad Católica, Santiago, Chile), my secondary DPhil supervisor Prof Anthony Dickenson (University College London) and Prof Andrew Todd (University of Glasgow).
As of 2017, I am neuroscience tutor to undergraduate medical students at Lady Margaret Hall.
McDermott LA. et al, (2019), Neuron, 101, 905 - 919.e8
Dawes JM. et al, (2018), Neuron, 97, 806 - 822.e10