Contact information
Colleges
Ludo van Hillegondsberg
MBChB, MSc, MRCP
Clinical Research Fellow | DPhil Student
Biography
Ludo van Hillegondsberg is a clinical research fellow and DPhil student with the Oxford Parkinson's Disease Centre (OPDC) and the Oxford-GSK Institute of Molecular and Computational Medicine (IMCM).
Ludo attained his medical degree in 2016 at Stellenbosch University. During his subsequent MSc in Clinical Neurosciences at University College London he developed an interest in neurodegenerative disease. In May 2023 he joined the OPDC and IMCM as a clinical research fellow and started his DPhil in Clinical Neurosciences in September 2023. His current research – utilising the deeply phenotyped OPDC Discovery cohort of manifest and prodromal PD – focuses on integrating clinical data with proteomic analysis to identify candidate biomarkers and biochemical characteristics that underpin cluster assignment and disease heterogeneity.
Key publications
Atypical Presentations of Huntington Disease‐like 2 in South African Individuals
Journal article
Narotam‐Jeena H. et al, (2024), Movement Disorders Clinical Practice, 11, 850 - 854
A quality improvement project on the collection and process of cerebrospinal fluid (CSF) for cytology
Conference paper
Liu AKL. et al, (2023), BRAIN PATHOLOGY, 33
Targeted next-generation sequencing identifies novel variants in candidate genes for Parkinson’s disease in Black South African and Nigerian patients
Journal article
Oluwole OG. et al, (2020), BMC Medical Genetics, 21
Alternating hemiplegia of childhood: First South African case report and verapamil as a possible treatment option
Journal article
Van Hillegondsberg LS. and Michaelis IA., (2019), South African Medical Journal, 109, 152 - 152
Using Eulerian video magnification to enhance detection of fasciculations in people with amyotrophic lateral sclerosis
Journal article
Van Hillegondsberg L. et al, (2017), Muscle & Nerve, 56, 1063 - 1067
Recent publications
Cholinergic degeneration in prodromal and early Parkinson’s disease: a link to present and future disease states
Journal article
Eisenstein T. et al, (2026), Brain, 149, 226 - 237
Smartphone-based prediction of dopaminergic deficit in prodromal and manifest Parkinson’s disease
Journal article
Gunter KM. et al, (2025), npj Digital Medicine, 8
Cholinergic white matter pathways integrity in prodromal and early manifest Lewy body disease
Journal article
Eisenstein T. et al, (2025), Brain Communications, 7
Atypical Presentations of Huntington Disease‐like 2 in South African Individuals
Journal article
Narotam‐Jeena H. et al, (2024), Movement Disorders Clinical Practice, 11, 850 - 854
A quality improvement project on the collection and process of cerebrospinal fluid (CSF) for cytology
Conference paper
Liu AKL. et al, (2023), BRAIN PATHOLOGY, 33