Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

Mandy Tseng

BSc, Cell Biology and Genetics


DPhil Student

Research groups

Research

I am a DPhil student in the Neural Injury Group, under the supervision of Prof. David Bennett, Prof. Sarosh Irani, and A/Prof. John Dawes. I am studying the role of CASPR2, a known target of autoantibodies, in neuropathic pain. My project aims to:

I) Investigate the mechanism of action of CASPR2 autoantibodies in the pathophysiology of neuropathic pain; 

ii) Understand the effect of CASPR2 overexpression on neuropathic pain in preclinical models; and 

iii) Explore whether increasing CASPR2 expression in sensory neurons is a feasible treatment for neuropathic pain.

Prior to my graduate studies, I obtained my B.Sc. in Cell Biology from the University of British Columbia. I then joined the antibody discovery group in Amgen, where I worked on the generation of therapeutic antibodies toward ion channels and complex membrane proteins.

Social media