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Marco Pisa
Senior Multiple Sclerosis Fellow and Clinical Neurosciences DPhil student
Biography
Dr. Marco Pisa is a neurologist with a special interest in Multiple Sclerosis. He received his medical and neurology training at San Raffaele Hospital, Milan (Italy), where he acquired comprehensive expertise in the field of MS diagnosis and treatment under the mentorship of world-leading MS physicians, Prof. Comi and Prof. Filippi, while serving as a senior registrar and locum consultant. He then moved to the University of Oxford, supported by the Oxford-Quinnipiac partnership and a prestigious scholarship from the Clarendon Fund, to work as a Senior MS Clinical and Research Fellow and a DPhil student under Prof. De Luca. He is also involved in undergraduate medical education and serves as Specialist Clinical Advisor at Trinity College, Oxford.
His research journey commenced with a focus on biomarkers aimed at tracking MS progression. He has made significant contributions to the field, with notable publications encompassing clinical studies, neurophysiological research (including Transcranial Magnetic Stimulation, Optical Coherence Tomography, and Evoked Potentials), and fluid biomarkers. In an attempt to delve into the complexity of the molecular determinants of neurodegeneration, he started a DPhil on the neuropathology of progressive MS, the findings of which have been acknowledged by the recent Early Career Researcher Prize at the Nuffield Department of Clinical Neurosciences, University of Oxford.
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Recent publications
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Neuropathological Evidence of Reduced Amyloid Beta and Neurofibrillary Tangles in Multiple Sclerosis Cortex
Journal article
Pansieri J. et al, (2025), Annals of Neurology
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The Effects of Disease‐Modifying Therapies on Optic Nerve Degeneration in Multiple Sclerosis
Journal article
Zhang X. et al, (2025), European Journal of Neurology, 32
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Aberrant iron deposition in the multiple sclerosis spinal cord relates to neurodegeneration
Preprint
Pisa M. et al, (2024)
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Neuroaxonal damage in natalizumab-treated MS patients: The role of JCV antibody titres
Journal article
Dalla Costa G. et al, (2024), Multiple Sclerosis Journal, 30, 1561 - 1565
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Retinal Changes in Double-Antibody Seronegative Neuromyelitis Optica Spectrum Disorders
Conference paper
Oertel FC. et al, (2024), Neurology Neuroimmunology & Neuroinflammation, 11