Emeritus Professor of Neuropathology
Research activities are mainly in fields related to the use of brain tissue in the Thomas Willis Oxford Brain Collection, including many cases of dementia and elderly controls and multiple sclerosis. In dementia current interest centres on determining to what extent, and in what way, cerebrovascular disease contributes to dementia. In multiple sclerosis I collaborate with Dr DeLuca in understanding the manner in which genetic variables in multiple sclerosis translate into pathological changes in the brain and spinal cord in that disease.
Sources of Funding
- Alzheimer’s Brain Bank UK 2008- 2013
- Austica 2009- 2012
Awards Training and Qualifications
- BA Physiology Oxford 1963
- BM BCh Oxford 1967
- Bsc Oxford 1969
Anterior optic pathway pathology in demyelinating CNS diseases
Pisa M. et al, (2020), NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 46, 30 - 31
Perivascular astrocyte expression in the multiple sclerosis motor cortex
Yee SA. et al, (2020), NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY, 46, 44 - 44
Target Tau, not Amyloid, to Prevent and Treat Alzheimer’s Disease
Esiri MM., (2020), OBM Geriatrics, 4
Cell Senescence and Cerebral Small Vessel Disease in the Brains of People Aged 80 Years and Older.
Norton EJ. et al, (2019), J Neuropathol Exp Neurol, 78, 1066 - 1072
Relating diffusion tensor imaging measurements to microstructural quantities in the cerebral cortex in multiple sclerosis.
McKavanagh R. et al, (2019), Hum Brain Mapp, 40, 4417 - 4431