Maria Isabel Leite

• Chronic neuropathic pain severity is determined by lesion level in aquaporin 4-antibody-positive myelitis.

  Tackley G. et al, (2017), J Neurol Neurosurg Psychiatry, 88, 165 - 169

• Pain in patients with transverse myelitis and its relationship to aquaporin 4 antibody status.

  Kong Y. et al, (2016), J Neurol Sci, 368, 84 - 88

• Epidemiology of myasthenia gravis in Northern Portugal: Frequency estimates and clinical epidemiological distribution of cases.

  Santos E. et al, (2016), Muscle Nerve, 54, 413 - 421

• Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at s =13 TeV using the ATLAS detector

  Aaboud M. et al, (2016), Physical Review D, 94

• Pregnancy outcomes in aquaporin-4-positive neuromyelitis optica spectrum disorder.

  Nour MM. et al, (2016), Neurology, 86, 79 - 87

• Predictive value of MRI parameters in severity and recovery of first-episode myelitis in aquaporin-4 antibody disease.

  Murchison A. et al, (2015), J Neurol Sci, 355, 49 - 53

• Update on biomarkers in neuromyelitis optica.

  Melamed E. et al, (2015), Neurol Neuroimmunol Neuroinflamm, 2

• Aquaporin-4 antibody isoform binding specificities do not explain clinical variations in NMO.

  Kitley J. et al, (2015), Neurol Neuroimmunol Neuroinflamm, 2

• Use of Advanced Magnetic Resonance Imaging Techniques in Neuromyelitis Optica Spectrum Disorder.

  Kremer S. et al, (2015), JAMA Neurol, 72, 815 - 822

• Whippits, nitrous oxide and the dangers of legal highs.

  Thompson AG. et al, (2015), Pract Neurol, 15, 207 - 209

• Myasthenia gravis: Association of British Neurologists' management guidelines.

  Sussman J. et al, (2015), Pract Neurol, 15, 199 - 206

• MOG cell-based assay detects non-MS patients with inflammatory neurologic disease.

  Waters P. et al, (2015), Neurol Neuroimmunol Neuroinflamm, 2

• Demographic and clinical features of neuromyelitis optica: A review.

  Pandit L. et al, (2015), Mult Scler, 21, 845 - 853

• Clinical Features and Diagnostic Usefulness of Antibodies to Clustered Acetylcholine Receptors in the Diagnosis of Seronegative Myasthenia Gravis.

  Rodríguez Cruz PM. et al, (2015), JAMA Neurol, 72, 642 - 649

• A 41-year-old woman with acute weakness and encephalopathy associated with MOG antibodies.

  Morris KA. et al, (2015), Neurol Neuroimmunol Neuroinflamm, 2

• Paediatric neuromyelitis optica: Clinical, MRI of the brain and prognostic features

  Absoud M. et al, (2015), Journal of Neurology, Neurosurgery and Psychiatry, 86, 470 - 472

• Paediatric neuromyelitis optica: clinical, MRI of the brain and prognostic features.

  Absoud M. et al, (2015), J Neurol Neurosurg Psychiatry, 86, 470 - 472

• Anti-MOG antibodies with longitudinally extensive transverse myelitis preceded by CLIPPERS.

  Symmonds M. et al, (2015), Neurology, 84, 1177 - 1179

• Collagen Q--a potential target for autoantibodies in myasthenia gravis.

  Zoltowska Katarzyna M. et al, (2015), J Neurol Sci, 348, 241 - 244

• Predictive value of MRI parameters in severity and recovery of first-episode myelitis in aquaporin-4 antibody disease

  Murchison A. et al, (2015), Journal of the Neurological Sciences, 355, 49 - 53

• Collagen Q - A potential target for autoantibodies in myasthenia gravis

  Zoltowska Katarzyna M. et al, (2015), Journal of the Neurological Sciences, 348, 241 - 244

• Opportunistic infections of the retina in patients with aquaporin-4 antibody disease.

  George JS. et al, (2014), JAMA Neurol, 71, 1429 - 1432

• Longstanding complex regional pain syndrome is associated with activating autoantibodies against alpha-1a adrenoceptors.

  Dubuis E. et al, (2014), Pain, 155, 2408 - 2417

• Clinical and serological study of myasthenia gravis using both radioimmunoprecipitation and cell-based assays in a South Asian population

  Chang T. et al, (2014), Journal of the Neurological Sciences, 343, 82 - 87

• Clinical and serological study of myasthenia gravis using both radioimmunoprecipitation and cell-based assays in a South Asian population.

  Chang T. et al, (2014), J Neurol Sci, 343, 82 - 87

• Glycine receptor antibodies in PERM and related syndromes: characteristics, clinical features and outcomes.

  Carvajal-González A. et al, (2014), Brain, 137, 2178 - 2192

• Glycine receptor antibodies in 2 cases of new, adult-onset epilepsy.

  Zuliani L. et al, (2014), Neurol Neuroimmunol Neuroinflamm, 1

• Characterization of neuromyelitis optica and neuromyelitis optica spectrum disorder patients with a late onset.

  Collongues N. et al, (2014), Mult Scler, 20, 1086 - 1094

• Time to next relapse as a primary endpoint in neuromyelitis optica clinical trials.

  Kitley J. et al, (2014), J Neurol Neurosurg Psychiatry, 85, 589 - 590

• Catastrophic brain relapse in seronegative NMO after a single dose of natalizumab.

  Kitley J. et al, (2014), J Neurol Sci, 339, 223 - 225

• Catastrophic brain relapse in seronegative NMO after a single dose of natalizumab

  Kitley J. et al, (2014), Journal of the Neurological Sciences, 339, 223 - 225

• Neuromyelitis optica spectrum disorders with aquaporin-4 and myelin-oligodendrocyte glycoprotein antibodies: a comparative study.

  Kitley J. et al, (2014), JAMA Neurol, 71, 276 - 283

• Distinction between MOG antibody-positive and AQP4 antibody-positive NMO spectrum disorders.

  Sato DK. et al, (2014), Neurology, 82, 474 - 481

• Longitudinally extensive transverse myelitis with and without aquaporin 4 antibodies.

  Kitley J. et al, (2013), JAMA Neurol, 70, 1375 - 1381

• Neuromyelitis optica IgG causes placental inflammation and fetal death.

  Saadoun S. et al, (2013), J Immunol, 191, 2999 - 3005

• Methotrexate is an alternative to azathioprine in neuromyelitis optica spectrum disorders with aquaporin-4 antibodies.

  Kitley J. et al, (2013), J Neurol Neurosurg Psychiatry, 84, 918 - 921

• Seronegative NMO: a sensitive AQP4 antibody test clarifies clinical features and next challenges.

  Fujihara K. and Leite MI., (2013), Neurology, 80, 2176 - 2177

• Distinction of seropositive NMO spectrum disorder and MS brain lesion distribution.

  Matthews L. et al, (2013), Neurology, 80, 1330 - 1337

• Progressive encephalomyelitis with rigidity and myoclonus: the first pediatric case with glycine receptor antibodies.

  Damásio J. et al, (2013), JAMA Neurol, 70, 498 - 501

• Targeting ASIC1 in primary progressive multiple sclerosis: evidence of neuroprotection with amiloride.

  Arun T. et al, (2013), Brain, 136, 106 - 115

• Targeting ASIC1 in primary progressive multiple sclerosis: Evidence of neuroprotection with amiloride

  Arun T. et al, (2013), Brain, 136, 106 - 115

• Progressive encephalomyelitis with rigidity and myoclonus: a syndrome with diverse clinical features and antibody responses.

  Shugaiv E. et al, (2013), Eur Neurol, 69, 257 - 262

• Methotrexate is an alternative to azathioprine in neuromyelitis optica spectrum disorders with aquaporin-4 antibodies

  Kitley J. et al, (2013), Journal of Neurology, Neurosurgery and Psychiatry, 84, 918 - 921

• The search for new antigenic targets in myasthenia gravis.

  Cossins J. et al, (2012), Ann N Y Acad Sci, 1275, 123 - 128

• Antibodies identified by cell-based assays in myasthenia gravis and associated diseases.

  Vincent A. et al, (2012), Ann N Y Acad Sci, 1274, 92 - 98

• Treatment of neuromyelitis optica: Review and recommendations

  Kimbrough DJ. et al, (2012), Multiple Sclerosis and Related Disorders, 1, 180 - 187

• Treatment of Neuromyelitis Optica: Review and Recommendations.

  Kimbrough DJ. et al, (2012), Mult Scler Relat Disord, 1, 180 - 187

• Myelin-oligodendrocyte glycoprotein antibodies in adults with a neuromyelitis optica phenotype.

  Kitley J. et al, (2012), Neurology, 79, 1273 - 1277

• Presence and pathogenic relevance of antibodies to clustered acetylcholine receptor in ocular and generalized myasthenia gravis.

  Jacob S. et al, (2012), Arch Neurol, 69, 994 - 1001

• Glycine receptor antibodies are detected in progressive encephalomyelitis with rigidity and myoclonus (PERM) but not in saccadic oscillations.

  Iizuka T. et al, (2012), J Neurol, 259, 1566 - 1573

• A practical guide to the treatment of neuromyelitis optica.

  Palace J. et al, (2012), Pract Neurol, 12, 209 - 214

• Prognostic factors and disease course in aquaporin-4 antibody-positive patients with neuromyelitis optica spectrum disorder from the United Kingdom and Japan.

  Kitley J. et al, (2012), Brain, 135, 1834 - 1849

• Myasthenia gravis and neuromyelitis optica spectrum disorder: a multicenter study of 16 patients.

  Leite MI. et al, (2012), Neurology, 78, 1601 - 1607

• Influence of pregnancy on neuromyelitis optica spectrum disorder.

  Kim W. et al, (2012), Neurology, 78, 1264 - 1267

• Passive and active immunization models of MuSK-Ab positive myasthenia: electrophysiological evidence for pre and postsynaptic defects.

  Viegas S. et al, (2012), Exp Neurol, 234, 506 - 512

• Diagnosis of neuromyelitis optica (NMO) spectrum disorders: is MRI obsolete?

  Downer JJ. et al, (2012), Neuroradiology, 54, 279 - 285

• Diagnosis of neuromyelitis optica (NMO) spectrum disorders: Is MRI obsolete?

  Downer JJ. et al, (2012), Neuroradiology, 54, 279 - 285

• The differential diagnosis of longitudinally extensive transverse myelitis.

  Kitley JL. et al, (2012), Mult Scler, 18, 271 - 285

• Myelin water imaging reflects clinical variability in multiple sclerosis.

  Kolind S. et al, (2012), Neuroimage, 60, 263 - 270

• Myelin water imaging reflects clinical variability in multiple sclerosis

  Kolind S. et al, (2012), NeuroImage, 60, 263 - 270

• Serologic diagnosis of NMO: a multicenter comparison of aquaporin-4-IgG assays.

  Waters PJ. et al, (2012), Neurology, 78, 665 - 671

• Prognostic factors and disease course in aquaporin-4 antibody-positive patients with neuromyelitis optica spectrum disorder from the United Kingdom and Japan

  Kitley J. et al, (2012), Brain, 135, 1834 - 1849

• A case of glycine-receptor antibody-associated encephalomyelitis with rigidity and myoclonus (PERM): clinical course, treatment and CSF findings.

  Piotrowicz A. et al, (2011), J Neurol, 258, 2268 - 2270

• Progressive encephalomyelitis with rigidity and myoclonus: glycine and NMDA receptor antibodies.

  Turner MR. et al, (2011), Neurology, 77, 439 - 443

• Use of mitoxantrone in neuromyelitis optica.

  Kitley JL. et al, (2011), Arch Neurol, 68

• The passive transfer of immunoglobulin G serum antibodies from patients with longstanding Complex Regional Pain Syndrome.

  Goebel A. et al, (2011), Eur J Pain, 15, 504.e1 - 504.e6

• Non-radioactive serological diagnosis of myasthenia gravis and clinical features of patients from Tianjin, China.

  Yang L. et al, (2011), J Neurol Sci, 301, 71 - 76

• Progressive encephalomyelitis with rigidity and myoclonus: resolution after thymectomy.

  Clerinx K. et al, (2011), Neurology, 76, 303 - 304

• Glycine receptor antibodies are detected in progressive encephalomyelitis with rigidity and myoclonus (PERM) but not in saccadic oscillations

  Iizuka T. et al, (2011), Journal of Neurology, 1 - 8

• Cerebral Vasculitis

  Scolding NJ. et al, (2010), 1, 485 - 489

• Thymoma and paraneoplastic myasthenia gravis.

  Marx A. et al, (2010), Autoimmunity, 43, 413 - 427

• Interferon Beta treatment in neuromyelitis optica: increase in relapses and aquaporin 4 antibody titers.

  Palace J. et al, (2010), Arch Neurol, 67, 1016 - 1017

• Diagnostic use of autoantibodies in myasthenia gravis.

  Leite MI. et al, (2010), Autoimmunity, 43, 371 - 379

• Chronic mucocutaneous candidiasis in APECED or thymoma patients correlates with autoimmunity to Th17-associated cytokines.

  Kisand K. et al, (2010), J Exp Med, 207, 299 - 308

• Symptomatic, radiological and pathological involvement of the hypothalamus in neuromyelitis optica.

  Viegas S. et al, (2009), J Neurol Neurosurg Psychiatry, 80, 679 - 682

• The ageing and myasthenic thymus: a morphometric study validating a standard procedure in the histological workup of thymic specimens.

  Ströbel P. et al, (2008), J Neuroimmunol, 201-202, 64 - 73

• IgG1 antibodies to acetylcholine receptors in 'seronegative' myasthenia gravis.

  Leite MI. et al, (2008), Brain, 131, 1940 - 1952

• Aquaporin-4 antibodies in neuromyelitis optica and longitudinally extensive transverse myelitis.

  Waters P. et al, (2008), Arch Neurol, 65, 913 - 919

• Myasthenia gravis seronegative for acetylcholine receptor antibodies.

  Vincent A. et al, (2008), Ann N Y Acad Sci, 1132, 84 - 92

• Autoimmunizing mechanisms in thymoma and thymus.

  Willcox N. et al, (2008), Ann N Y Acad Sci, 1132, 163 - 173

• Myasthenia gravis thymus: complement vulnerability of epithelial and myoid cells, complement attack on them, and correlations with autoantibody status.

  Leite MI. et al, (2007), Am J Pathol, 171, 893 - 905

• The role of HLA-DRB1 alleles on susceptibility and outcome of a Portuguese Multiple Sclerosis population.

  Silva AM. et al, (2007), J Neurol Sci, 258, 69 - 74

• Neuromuscular junction autoimmune disease: muscle specific kinase antibodies and treatments for myasthenia gravis.

  Vincent A. and Leite MI., (2005), Curr Opin Neurol, 18, 519 - 525

• Fewer thymic changes in MuSK antibody-positive than in MuSK antibody-negative MG.

  Leite MI. et al, (2005), Ann Neurol, 57, 444 - 448

• A whole genome association study in multiple sclerosis patients from north Portugal.

  Martins Silva B. et al, (2003), J Neuroimmunol, 143, 116 - 119

• [Neurological involvement in pre-eclampsia/eclampsia: the role of neuroimaging].

  Marques R. et al, (1997), Acta Med Port, 10, 585 - 588

• Spontaneous thoracolumbar spinal cord infarction: report of six cases.

  Monteiro L. et al, (1992), Acta Neurol Scand, 86, 563 - 566

• [The elderly patient at the General Hospital of Santo António. Analysis of one year of admissions].

  Lima B. et al, (1990), Acta Med Port, 3, 269 - 272

Recent Publications

• Chronic neuropathic pain severity is determined by lesion level in aquaporin 4-antibody-positive myelitis.

  Tackley G. et al, (2017), J Neurol Neurosurg Psychiatry, 88, 165 - 169

• Pain in patients with transverse myelitis and its relationship to aquaporin 4 antibody status.

  Kong Y. et al, (2016), J Neurol Sci, 368, 84 - 88

• Epidemiology of myasthenia gravis in Northern Portugal: Frequency estimates and clinical epidemiological distribution of cases.

  Santos E. et al, (2016), Muscle Nerve, 54, 413 - 421

• Search for new phenomena in final states with an energetic jet and large missing transverse momentum in pp collisions at s =13 TeV using the ATLAS detector

  Aaboud M. et al, (2016), Physical Review D, 94

• Pregnancy outcomes in aquaporin-4-positive neuromyelitis optica spectrum disorder.

  Nour MM. et al, (2016), Neurology, 86, 79 - 87