Pao-Sheng Chang

BSc Life Science, National Tsing Hua University
MRes Translational Neurology, UCL
DPhil Clinical Neurosciences, University of Oxford

Dr. Pao-Sheng (Paul) is a highly motivated neuroimmunologist with 12 years of research experience and solid scientific training particularly during his DPhil and postdoc periods at NDCN, University of Oxford.

During his DPhil, he developed high-throughput multiplex live cell-based flow cytometry assays to detect autoantibodies in patients with autoimmune-mediated neurological disorders. As a postdoc, he has investigated the neuroimmunological signatures inside human injured nerve tissues through RNA sequencing and protein-based fluorescent labelling. The single-cell RNA sequencing works are done with the collaborators at Oxford Kennedy Institute and King's College London. Also, he has established a humanised in vitro microfluidic neuro-immune coculture platform to evaluate the excitability of human sensory neurons. Both his DPhil and postdoctoral projects are highly translational and applicable.

Furthermore, he was involved in a start-up company: Neurolytic Healthcare (now Mable), as a research analyst to offer intellectual expertise, and he had biomedical consulting experience to support Ogenblik Ltd. securing a £120k innovation grant.

Paul’s vocation is to translate the promising biomedical discoveries into effective therapeutic interventions to heal the patients in need.