Shuaiwei Wang

After completing his Bachelor’s degree at Jilin University, Shuaiwei Wang studied the molecular regulation of regulatory T cells (Tregs) and autoimmune disease at Institut Pasteur of Shanghai. After obtaining his Master’s degree, he completed his PhD project with Dr. Serge van de Pavert at CIML (Centre d’immunologie de Marseille-Luminy) in France.

During his PhD training, he studied the innate lymphoid cells (ILCs) in ischemic stroke brain. By taking advantage of 3D immunofluorescence on the whole brain, he identified the presence and location of ILCs in the stroke brain lesion. The ILCs numbers at different time points were quantified by flow cytometry, the majority of which were NK cells. By using genetic mouse models, he determined that CXCL12-CXCR4-mediated chemotaxis is indispensable for the infiltration of NK cells in the ischemic brain lesion. He then showed that NK cells is beneficial for the motor recovery from ischemic stroke.

With the aim of further understanding the crosstalk between immune cells and nervous system, he has been working on the immunity in periphery nerve injury at the University of Oxford.